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Patient preferences and willingness to pay for innovations in intermittent self-catheters

机译：病人的偏好和愿意为间歇性自我导管的创新付费

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Background: Intermittent catheterization is the gold standard for bladder management in Europe in people with spinal cord injuries. The aim of the present study was to identify and investigate individuals’ preferences regarding intermittent self-catheterization (ISC) devices and furthermore investigate the willingness to pay for attributes in ISC devices in the UK, France, and the Netherlands.Methods: A discrete choice experiment survey was conducted to evaluate the patients’ perceived value of catheter features. Attributes were selected based upon a literature review of the most important characteristics of catheters and the survey was developed and validated with input from patients and medical experts. Data were analyzed using the conditional logit model whereby the coefficients obtained from the model provided an estimate of the (log) odds ratios of preference for attributes. Willingness to pay was estimated for all levels of the attributes.Results: Two-hundred and eighty-three participants completed the questionnaire and were included in data analysis. Risk of infection had the highest odds ratios as preferred important attribute for all three countries followed by ease of insertion. “Pre-coated catheters” was found to be valued as the most preferred coating technology across all countries. Out of pocket cost was a significant influence on patients’ choice.Conclusion: Users of ISC perceive the value of convenience (size of catheter), ease of insertion, and reduced risk of infection as the most important features attached to an intermittent catheter. These results are applicable both for the “classic” ISC user as well as for another broad group of catheter dependent individuals.
机译：背景：间歇性导管插入术是欧洲脊髓损伤患者膀胱管理的金标准。本研究的目的是确定和调查个人对间歇性自导管（ISC）设备的偏好，并进一步调查在英国，法国和荷兰的ISC设备中为属性支付的意愿。进行实验调查以评估患者对导管特征的感知价值。根据对导管最重要特征的文献综述来选择属性，并根据患者和医学专家的意见进行调查并进行验证。使用条件对数模型分析数据，由此从模型获得的系数提供了对属性偏好的（对数）优势比的估计。结果：对所有级别的属性的支付意愿进行了评估。结果：203名参与者完成了问卷调查，并纳入了数据分析。感染的风险是所有三个国家的首选重要属性，比值比最高，其次是插入。人们发现“预涂层导管”被认为是所有国家/地区首选的涂层技术。自付费用对患者的选择产生了重大影响。结论：ISC的使用者将便利性（导管的大小），易于插入和降低感染风险的价值视为间歇导管所具有的最重要特征。这些结果既适用于“经典” ISC用户，也适用于另一类广泛的导管依赖患者。

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