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首页> 外文期刊>Pediatric Dental Journal >Warmed acidulated phosphate fluoride enhances release of fluoride from human enamel surfaces, promoting lesion remineralization in vitro and in situ
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Warmed acidulated phosphate fluoride enhances release of fluoride from human enamel surfaces, promoting lesion remineralization in vitro and in situ

机译：温暖的酸性磷酸根氟化物可增强人类牙釉质表面的氟化物释放，促进病变在体外和原位再矿化

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Background: The calcium fluoride-like material deposited on the enamel surface is important as a fluoride reservoir. Elevated temperatures significantly increase the acquisition of KOH-soluble fluoride on sound tooth surfaces in vitro. Methods: We investigated the efficacy of warmed APF solution on remineralization of subsurface enamel lesions, both in vitro and in situ. Hardness recovery was measured every week for 4 weeks to assess remineralization efficacy, and the behavior of fluoride release from sound and demineralized enamel with APF solution applied at 25 ^oC and 50^oC was compared. Results: Application of APF to enamel at 50 ^oC showed a significantly greater degree of F^- release up to 18 h than the 25 ^oC group in sound specimens and up to 48 h in demineralized specimens. Moreover, longer-lasting and greater amounts of F^- release were observed in demineralized specimens versus sound specimens. The profiles of changes in hardness over time in vitro and in situ showed that the hardness was significantly greater in the 50 ^oC group than in the 25 ^oC and control groups at all measurement points and the mean value of the hardness recovery in the 25 ^oC and 50 ^oC groups was observed by 2 weeks, although a significant increase was only noted from baseline to 1 week in the 25 ^oC group. Overall, the recovery of hardness was inadequate, compared to the original enamel. Conclusion: In conclusion, application of the warmed APF solution to the demineralized enamel lesion showed potential to increase the fluoride release and enhance the rate of remineralization than that at 25 ^oC.
机译：背景：沉积在牙釉质表面的类氟化钙材料很重要，它是氟化物的储存库。升高的温度显着增加了体外健全牙齿表面上KOH可溶性氟化物的获取。方法：我们研究了温热的APF溶液在体外和原位对再矿化地下釉质病变的功效。每周测量硬度恢复情况，持续4周，以评估再矿化功效，并比较在25℃和50℃下使用APF溶液从健全的软化瓷釉中释放氟化物的行为。结果：在声音样品中，在25℃下，APF在搪瓷标本中的释放速率在25℃下显着高于在50℃时显着提高，而在软化标本中则在48 h时，在搪瓷中施加F ^-的程度明显更高。此外，在脱矿物质的样品中，观察到的F 2+释放持续时间更长，而声音样品则更多。体外和原位硬度随时间的变化曲线表明，在所有测量点，50 ^ oC组的硬度均显着高于25 ^ oC和对照组的硬度，而25℃下的硬度恢复平均值在2周时观察到^ oC和50 ^ oC组，尽管在25 ^ oC组中仅从基线到1周才观察到显着增加。总体而言，与原始搪瓷相比，硬度的恢复不足。结论：总之，将温热的APF溶液应用于脱矿质的牙釉质病变显示出比25℃时增加氟化物释放并提高再矿化率的潜力。

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