Fixation using alternative implants for the treatment of hip fractures (FAITH-2): design and rationale for a pilot multi-centre 2?×?2 factorial randomized controlled trial in young femoral neck fracture patients

Gerard P. Slobogean; Sheila Sprague; Sofia Bzovsky; Diane Heels-Ansdell; Lehana Thabane; Taryn Scott; Mohit Bhandari

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Fixation using alternative implants for the treatment of hip fractures (FAITH-2): design and rationale for a pilot multi-centre 2?×?2 factorial randomized controlled trial in young femoral neck fracture patients

机译：使用替代植入物固定治疗髋部骨折（FAITH-2）：年轻的股骨颈骨折患者多中心2？×？2因子析因随机对照试验的设计和原理

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BackgroundFemoral neck fractures in patients ≤?60?years of age are often very different injuries compared to low-energy, hip fractures in elderly patients and are difficult to manage because of inherent problems associated with high-energy trauma mechanisms and increased functional demands for recovery. Internal fixation, with multiple cancellous screws or a sliding hip screw (SHS), is the most common treatment for this injury in young patients. However, there is no clinical consensus regarding which surgical technique is optimal. Additionally, there is compelling rationale to use vitamin D supplementation to nutritionally optimize bone healing in young patients. This pilot trial will determine feasibility and provide preliminary clinical data for a larger definitive trial.

机译：背景年龄≤60岁的患者的股骨颈骨折与低能量，老年患者的髋部骨折相比通常是非常不同的损伤，并且由于与高能量创伤机制相关的内在问题以及对康复的功能需求增加而难以管理。对于年轻患者，这种损伤最常见的治疗方法是采用多个松质螺钉或滑动髋螺钉（SHS）进行内固定。但是，关于哪种手术技术是最佳的，尚无临床共识。另外，有令人信服的理由是使用维生素D补充剂可以在营养上优化年轻患者的骨骼愈合。该初步试验将确定可行性，并为较大的最终试验提供初步的临床数据。

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《Pilot and Feasibility Studies》 |2019年第1期|共14页
作者
Gerard P. Slobogean; Sheila Sprague; Sofia Bzovsky; Diane Heels-Ansdell; Lehana Thabane; Taryn Scott; Mohit Bhandari;
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中图分类工程基础科学;
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Clinical protocolsFemoral neck fracturesFracture fixationinternalVitamin DRandomized controlled trial;

机译：临床方案股骨颈骨折骨折固定术内部维生素随机对照试验;

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1. Fixation using alternative implants for the treatment of hip fractures (FAITH): design and rationale for a multi-centre randomized trial comparing sliding hip screws and cancellous screws on revision surgery rates and quality of life in the treatment of femoral neck fractures [J] . The FAITH Investigators BMC Musculoskeletal Disorders . 2014,第1期

机译：使用替代植入物固定治疗髋部骨折的方法（FAITH）：一项多中心随机试验的设计和原理，比较了滑动髋螺钉和松质螺钉对股骨颈骨折的翻修手术率和生活质量
2. Rationale and design of the HIP fracture Accelerated surgical TreaTment And Care tracK (HIP ATTACK) Trial: a protocol for an international randomised controlled trial evaluating early surgery for hip fracture patients [J] . Flavia K Borges, Mohit Bhandari, Ameen Patel, BMJ Open . 2019,第4期

机译：HIP骨折加速外科治疗和护理追踪（HIP ATTACK）试验的原理和设计：一项评估髋部骨折患者早期手术的国际随机对照试验的方案
3. Ankle Injury Management (AIM): design of a pragmatic multi-centre equivalence randomised controlled trial comparing Close Contact Casting (CCC) to Open surgical Reduction and Internal Fixation (ORIF) in the treatment of unstable ankle fractures in patients over 60?years [J] . Keith Willett, David J Keene, Lesley Morgan, BMC Musculoskeletal Disorders . 2014,第1期

机译：踝关节损伤管理（AIM）：一项实用的多中心等效性随机对照试验设计，比较了近距离接触铸模（CCC）与开放手术复位和内固定（ORIF）治疗60岁以上患者不稳定的踝部骨折
4. External Fixation and Gait Assistive Device: New Combined Treatments for Patients with Femoral Neck Fractures [C] . M. Akai, K. Nakazawa, I. Ohnishi, International Society of Physical and Rehabilitation Medicine . 2007

机译：外固定和步态辅助装置：股骨颈骨折患者的新组合治疗
5. Fixation using alternative implants for the treatment of hip fractures (FAITH-2): design and rationale for a pilot multi-centre 2 × 2 factorial randomized controlled trial in young femoral neck fracture patients [O] . Gerard P. Slobogean, Sheila Sprague, Sofia Bzovsky, 2019

机译：使用替代植入物固定治疗髋部骨折（FAITH-2）：年轻的股骨颈骨折患者多中心2×2析因随机对照试验的设计和原理
6. Fixation Using Alternative Implants for the Treatment of Hip Fractures (FAITH-2): The Clinical Outcomes of a Multicenter 2 × 2 Factorial Randomized Controlled Pilot Trial in Young Femoral Neck Fracture Patients [O] . Gerard P. Slobogean, Sheila Sprague, Sofia Bzovsky, 2020

机译：使用替代植入物用于治疗髋部骨折（Faith-2）的固定：在幼年股骨颈骨折患者中多中心2×2因子随机控制试验试验的临床结果

Fixation using alternative implants for the treatment of hip fractures (FAITH-2): design and rationale for a pilot multi-centre 2?×?2 factorial randomized controlled trial in young femoral neck fracture patients

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