Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study

Lauren E. Mokry; Stephanie Ross; Omar S. Ahmad; Vincenzo Forgetta; George Davey Smith; Aaron Leong; Celia M. T. Greenwood; George Thanassoulis; J. Brent Richards

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Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study

机译：维生素D与多发性硬化症的风险：孟德尔随机研究

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Background Observational studies have demonstrated an association between decreased vitamin D level and risk of multiple sclerosis (MS); however, it remains unclear whether this relationship is causal. We undertook a Mendelian randomization (MR) study to evaluate whether genetically lowered vitamin D level influences the risk of MS.

机译：背景观察性研究表明，维生素D水平降低与多发性硬化症（MS）风险之间存在关联。但是，目前尚不清楚这种关系是否是因果关系。我们进行了孟德尔随机（MR）研究，以评估遗传降低的维生素D水平是否会影响MS的风险。

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《PLoS Medicine》 |2015年第8期|共20页
作者
Lauren E. Mokry; Stephanie Ross; Omar S. Ahmad; Vincenzo Forgetta; George Davey Smith; Aaron Leong; Celia M. T. Greenwood; George Thanassoulis; J. Brent Richards;
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中图分类药学;
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1. Correction: Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study [J] . Lauren E. Mokry, Stephanie Ross, Omar S. Ahmad, PLoS Medicine . 2016,第3期

机译：校正：维生素D和多发性硬化症的风险：孟德尔随机研究
2. Mendelian randomization shows a causal effect of low vitamin D on multiple sclerosis risk [J] . Brooke Rhead, Maria B??rnhielm, Milena Gianfrancesco, Neurology: Genetics . 2016,第5期

机译：孟德尔随机化显示低维生素D对多发性硬化症风险的因果关系
3. Large differences in adiponectin levels have no clear effect on multiple sclerosis risk: A Mendelian randomization study [J] . Devorak Julia, Mokry Lauren E., Morris John A., Multiple sclerosis: clinical and laboratory research . 2017,第11期

机译：脂联素水平的巨大差异对多发性硬化风险没有明显影响：孟德利安随机化研究
4. Mendelian Randomization of Arsenic Metabolism as a Risk Factor for Hypertensive- and Diabetes-Related Traits among Adults in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) Cohort [C] . Molly Scannell Bryan, Tamar Sofer, Yasmin Mossavar-Rahmani, Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：在西班牙裔社区健康研究/拉丁裔（HCHS / SOL）队列研究中，孟德尔随机将砷代谢作为成人高血压和糖尿病相关性状的危险因素
5. A Double-Blind Randomized Intervention to Reduce Distress from Perceived Cognitive Impairment in Multiple Sclerosis [D] . Glusman, Morgan B. 2019

机译：一种双盲随机干预，以减少多发性硬化症中感知认知障碍的痛苦
6. Correction: Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study [O] . Lauren E. Mokry, Stephanie Ross, Omar S. Ahmad, 2016

机译：校正：维生素D和多发性硬化症的风险：孟德尔随机研究
7. Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study [O] . Mokry, Lauren E., Ross, Stephanie, Ahmad, Omar S., 2016

机译：维生素D与多发性硬化症的风险：孟德尔随机研究

Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study

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