High Parasitological Failure Rate of Visceral Leishmaniasis to Sodium Stibogluconate among HIV Co-infected Adults in Ethiopia

Ermias Diro; Lutgarde Lynen; Rezika Mohammed; Marleen Boelaert; Asrat Hailu; Johan van Griensven

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High Parasitological Failure Rate of Visceral Leishmaniasis to Sodium Stibogluconate among HIV Co-infected Adults in Ethiopia

机译：在埃塞俄比亚艾滋病毒合并感染的成年人中，内脏利什曼病对stibogluconate的寄生虫学失败率很高

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Background Antimonials are still being used for visceral leishmaniasis (VL) treatment among HIV co-infected patients in East-Africa due to the shortage of alternative safer drugs like liposomal amphotericin B. Besides tolerability, emergence of resistance to antimonials is a major concern.

机译：背景技术由于缺乏替代性更安全的药物（如脂质体两性霉素B），在东非的HIV合并感染患者中，抗生素仍被用于内脏利什曼病（VL）的治疗。除耐受性外，人们对抗生素的耐药性也是一个主要问题。

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《PLOS Neglected Tropical Diseases》 |2014年第5期|共9页
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Ermias Diro; Lutgarde Lynen; Rezika Mohammed; Marleen Boelaert; Asrat Hailu; Johan van Griensven;
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1. Ethiopian visceral leishmaniasis: generic and proprietary sodium stibogluconate are equivalent; HIV co-infected patients have a poor outcome. [J] . Ritmeijer K, msterdam.msf.org, Veeken H, Transactions of the Royal Society of Tropical Medicine and Hygiene . 2001,第6期

机译：埃塞俄比亚内脏利什曼病：普通葡糖酸钠和专有葡糖酸钠是等效的; HIV合并感染的患者预后较差。
2. A Comparison of Miltefosine and Sodium Stibogluconate for Treatment of Visceral Leishmaniasis in an Ethiopian Population with High Prevalence of HIV Infection [J] . Koert Ritmeijer, Abren Dejenie, Yibeltal Assefa, Clinical Infectious Diseases . 2006,第3期

机译：Miltefosine和Stibogluconate钠在高感染HIV的埃塞俄比亚人群中治疗内脏利什曼病的比较
3. Serological signatures of clinical cure following successful treatment with sodium stibogluconate in Ethiopian visceral leishmaniasis [J] . Gadisa Endalamaw, Tasew Geremew, Abera Adugna, Cytokine . 2017,第期

机译：在埃塞俄比亚内脏利山病成功治疗后临床治疗后的血清签名
4. Sodium Chlorate-Based Generation of Chlorine Dioxide Yields Improved Corrosion Rate Results and Fewer Equipment Failures Compared to Chlorine Treatment in a Cooling Systme [C] . Scott A. Marckini, Engineers Society of Western Pennsylvania International water conference annual meeting . 1996

机译：与冷却系统中的氯处理相比，氯酸钠产生的氯二氧化氯产生改善的腐蚀速率结果和更少的设备故障
5. The deadly crossroads: The role of household food insecurity and nutritional status in antiretroviral therapy (ART) outcomes; HIV+ adult treatment failure as an important public health challenge in sub-Saharan Africa, Ethiopia [D] . Jemal, Abdusebur 2009

机译：致命的十字路口：家庭粮食不安全和营养状况在抗逆转录病毒治疗（ART）结果中的作用；艾滋病毒+成人治疗失败是埃塞俄比亚撒哈拉以南非洲的重要公共卫生挑战
6. High Parasitological Failure Rate of Visceral Leishmaniasis to Sodium Stibogluconate among HIV Co-infected Adults in Ethiopia [O] . Ermias Diro, Lutgarde Lynen, Rezika Mohammed, 2014

机译：在埃塞俄比亚HIV合并感染的成年人内脏利什曼病的高寄生虫失败率对司糖葡糖酸钠
7. High parasitological failure rate of visceral leishmaniasis to sodium stibogluconate among HIV co-infected adults in Ethiopia. [O] . Ermias Diro, Lutgarde Lynen, Rezika Mohammed, 2014

机译：埃塞俄比亚HIV共感染成人中内脏利什曼病对葡萄糖酸钠的高寄生虫失败率。
8. Electron Microscopy of Leishmania donovani in Splenic Aspirates from Patients with Visceral Leishmaniasis during Treatment with Sodium Stibogluconate [R] . Chulay, J. D., Fawcett, D. W., Chunge, C. N. 1985

机译：杜氏葡萄糖酸钠治疗内脏利什曼病患者脾脏抽吸物中杜氏利什曼原虫的电子显微镜观察

High Parasitological Failure Rate of Visceral Leishmaniasis to Sodium Stibogluconate among HIV Co-infected Adults in Ethiopia

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