Expansion of Parasite-Specific CD4+ and CD8+ T Cells Expressing IL-10 Superfamily Cytokine Members and Their Regulation in Human Lymphatic Filariasis

Rajamanickam Anuradha; Parakkal Jovvian George; Luke E. Hanna; Paul Kumaran; Vedachalam Chandrasekaran; Thomas B. Nutman; Subash Babu

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Expansion of Parasite-Specific CD4+ and CD8+ T Cells Expressing IL-10 Superfamily Cytokine Members and Their Regulation in Human Lymphatic Filariasis

机译：表达IL-10超家族细胞因子成员的寄生虫特异性CD4 +和CD8 + T细胞的扩增及其在人淋巴丝虫病中的调控

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Background Lymphatic filariasis (LF) is known to be associated with an increased production of IL-10. The role of the other IL-10 family members in the pathogenesis of infection and/or disease is not known.

机译：背景已知淋巴丝虫病（LF）与IL-10的产生增加有关。其他IL-10家族成员在感染和/或疾病发病机理中的作用尚不清楚。

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《PLOS Neglected Tropical Diseases》 |2014年第4期|共13页
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Rajamanickam Anuradha; Parakkal Jovvian George; Luke E. Hanna; Paul Kumaran; Vedachalam Chandrasekaran; Thomas B. Nutman; Subash Babu;
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中图分类传染病;
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1. Interleukin-10- and Transforming Growth Factor β-Independent Regulation of CD8+ T Cells Expressing Type 1 and Type 2 Cytokines in Human Lymphatic Filariasis [J] . Rajamanickam Anuradha, Parakkal Jovvian George, Paul Kumaran, Clinical and vaccine immunology: CVI . 2014,第12期

机译：在人淋巴丝虫病中表达1型和2型细胞因子的CD8 + T细胞的白介素10和转化生长因子β依赖性调节
2. TGF-β cytokine signaling promotes CD8+ T cell development and low-affinity CD4+ T cell homeostasis by regulation of interleukin-7 receptor α expression [J] . OuyangW., OhS., MaQ., Immunity . 2013,第2期

机译：TGF-β细胞因子信号传导通过调节白介素7受体α表达促进CD8 + T细胞发育和低亲和力CD4 + T细胞稳态
3. Human peripheral blood CD4+ and CD8+ T cells express Th1-like cytokine mRNA and proteins following in vitro stimulation with heat-inactivated Brucella abortus. [J] . M B Zaitseva, H Golding, M Betts, Infection and immunity . 1995,第7期

机译：在用热灭活的布鲁氏菌流产体外刺激后，人外周血CD4 +和CD8 + T细胞表达Th1类细胞因子mRNA和蛋白质。
4. IMMUNIZATION OF DENDRITIC CELLS PULSED WITH PRRS VIRUS GP5 PROTEIN INDUCES CD4+ BUT NOT CD8+ T CELLS [C] . Nguyen-Dinh Quat, Jeongran Min, Jiwon Han, Congress ofthe International Pig Veterinary Society . 2008

机译：用PRRS病毒GP5蛋白脉冲树突细胞的免疫诱导CD4 +但不是CD8 + T细胞
5. Cytokine gene expression in CD4+ and CD8+ T cell subsets of chickens infected with Marek's disease virus. [D] . Parvizi, Payvand. 2008

机译：感染马立克氏病病毒的鸡的CD4 +和CD8 + T细胞亚群中的细胞因子基因表达。
6. Expansion of Parasite-Specific CD4+ and CD8+ T Cells Expressing IL-10 Superfamily Cytokine Members and Their Regulation in Human Lymphatic Filariasis [O] . Rajamanickam Anuradha, Parakkal Jovvian George, Luke E. Hanna, 2014

机译：表达IL-10超家族细胞因子成员的寄生虫特异性CD4 +和CD8 + T细胞的扩增及其在人淋巴丝虫病中的调控
7. Expansion of parasite-specific CD4+ and CD8+ T cells expressing IL-10 superfamily cytokine members and their regulation in human lymphatic filariasis. [O] . Rajamanickam Anuradha, Parakkal Jovvian George, Luke E Hanna, 2014

机译：表达IL-10超家族细胞因子成员的寄生虫特异性CD4 +和CD8 + T细胞的扩增及其在人淋巴丝虫病中的调节。
8. Induction in Humans of CD8+ and CD4+ T Cell and Antibody Responses by Sequential Immunization with Malaria DNA and Recombinant Protein [R] . Wang, R. , Epstein, J. , Charoenvit, Y. , 2004

机译：用疟疾DNa和重组蛋白连续免疫诱导人类对CD8 +和CD4 + T细胞及抗体的反应

Expansion of Parasite-Specific CD4+ and CD8+ T Cells Expressing IL-10 Superfamily Cytokine Members and Their Regulation in Human Lymphatic Filariasis

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