【24h】

A mind astray

机译:误入歧途

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摘要

He hadn't been able to dial the full number for some time. But he had told his family that the phone was out of order. Until one of his daughters realised that it was not the phone which was faulty but her father's memory. This is just one of the many manifestations of what could be the beginnings of Alzheimer's disease (AD). A disease which affects millions of people worldwide, and sends their families into a whirlpool of doubt, impatience, pain and disbelief. Slowly but surely, Alzheimer's takes a hold of the patient's brain, causing damage to its neuronal structure and hampering its cognitive faculties. In time, the patient fails to recognise his or her own family besides suffering from disturbed basic vital functions, and the family members have to learn to deal with the loss of someone dear who is still alive... With a little over 100 years of research into AD, scientists are now able to diagnose the affliction relatively early. Despite this, there is still no medication which can cure a patient, though researchers have ventured down many alleys. One of these alleys involves a protein known as immunophilin FKBP52 which may have a future in stalling the progression of Alzheimer's.
机译:他有一段时间无法拨打完整号码了。但是他告诉家人,电话坏了。直到他的一个女儿意识到那不是电话故障才是她父亲的记忆。这仅仅是阿尔茨海默氏病(AD)起源的众多表现之一。这种疾病影响着全球数百万人,并使他们的家人陷入怀疑,不耐烦,痛苦和难以置信的漩涡中。但可以肯定的是,阿尔茨海默氏症会慢慢抓住患者的大脑,从而损害其神经元结构并妨碍其认知能力。随着时间的流逝,患者除了遭受基本生命机能紊乱之外,还没有认识到自己的家人,家人必须学会应对仍然活着的亲人的遗体……距今已有100多年的历史。通过研究AD,科学家现在能够相对较早地诊断出这种疾病。尽管如此,尽管研究人员冒险沿许多小巷冒险,但仍然没有能够治愈患者的药物。这些小巷之一涉及一种称为亲免蛋白FKBP52的蛋白质,该蛋白质可能会阻止阿尔茨海默氏症的发展。

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