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首页> 外文期刊>Pulmonary Circulation >Quantitative Estimation of Right Ventricular Hypertrophy using ECG Criteria in Patients with Pulmonary Hypertension: A Comparison with Cardiac MRI:
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Quantitative Estimation of Right Ventricular Hypertrophy using ECG Criteria in Patients with Pulmonary Hypertension: A Comparison with Cardiac MRI:

机译：使用心电图标准对肺动脉高压患者的右心室肥大进行定量估计：与心脏MRI的比较：

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In patients with pulmonary arterial hypertension (PAH), right ventricular mass (RVM) correlates linearly with pulmonary artery pressure, and decreases with successful treatment. Accurate measurement of RVM currently requires cardiovascular magnetic resonance (CMR) imaging. We therefore tested the relationship between RVM and a simple, 12 lead ECG-derived value, the Butler-Leggett (BL) score. This has previously been validated in patients with RV hypertrophy (RVH) due to mitral stenosis. We also tested the diagnostic accuracy of the BL score in detecting RVH. The Scottish Pulmonary Vascular Unit database was reviewed retrospectively. Twenty-eight patients with PAH were identified, in whom CMR and ECG data had been recorded no more than 28 days apart. All had completed a comprehensive clinical assessment, including right heart catheterization. CMR-derived absolute RVM and RV mass index (RVMI=RV mass/LV mass) were correlated against BL score. The ability of this score to detect RVH was tested using 2 × 2 contingency tables. RVM and RVMI correlated with BL score (r=0.77, P0.001 and r=0.78, P0.001, respectively). A BL score 0.7 mV proved a highly specific but insensitive indicator of RVH, based on either absolute RVM (sensitivity 74%, specificity 100%) or a high RVMI (sensitivity 61%, specificity 100%). The BL score, which can be defined using a standard 12-lead ECG, correlates with RVM and RVMI in patients with PAH. A score 0.7 mV was a highly specific but insensitive indicator of RVH in these patients.
机译：在患有肺动脉高压（PAH）的患者中，右心室质量（RVM）与肺动脉压力呈线性关系，并随着治疗的成功而减少。 RVM的准确测量当前需要心血管磁共振（CMR）成像。因此，我们测试了RVM和一个简单的12导联心电图得出的值Butler-Leggett（BL）之间的关系。先前已在由于二尖瓣狭窄引起的RV肥大（RVH）的患者中对此进行了验证。我们还测试了BL评分在检测RVH中的诊断准确性。回顾性审查了苏格兰肺血管单位数据库。确定了28例PAH患者，其中记录的CMR和ECG数据间隔不超过28天。所有患者均已完成全面的临床评估，包括右心导管检查。 CMR衍生的绝对RVM和RV质量指数（RVMI = RV质量/ LV质量）与BL评分相关。使用2×2列联表测试了该分数检测RVH的能力。 RVM和RVMI与BL评分相关（分别为r = 0.77，P <0.001和r = 0.78，P <0.001）。基于绝对RVM（敏感性74％，特异性100％）或高RVMI（敏感性61％，特异性100％），BL得分> 0.7 mV被证明是RVH的高度特异性但不敏感的指标。可以使用标准的12导联ECG定义的BL评分与PAH患者的RVM和RVMI相关。在这些患者中，评分> 0.7 mV是RVH的高度特异性但不敏感的指标。

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