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首页> 外文期刊>The British journal of psychiatry : >Comorbid medical illness in bipolar disorder
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Comorbid medical illness in bipolar disorder

机译:躁郁症合并症

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Background Individuals with a mental health disorder appear to be at increased risk of medical illness. Aims To examine rates of medical illnesses in patients with bipolar disorder ( n = 1720) and to examine the clinical course of the bipolar illness according to lifetime medical illness burden. Method Participants recruited within the UK were asked about the lifetime occurrence of 20 medical illnesses, interviewed using the Schedules for Clinical Assessment in Neuropsychiatry (SCAN) and diagnosed according to DSM-IV criteria. Results We found significantly increased rates of several medical illnesses in our bipolar sample. A high medical illness burden was associated with a history of anxiety disorder, rapid cycling mood episodes, suicide attempts and mood episodes with a typically acute onset. Conclusions Bipolar disorder is associated with high rates of medical illness. This comorbidity needs to be taken into account by services in order to improve outcomes for patients with bipolar disorder and also in research investigating the aetiology of affective disorder where shared biological pathways may play a role.
机译:背景技术患有精神疾病的人似乎患病的风险增加。目的检查双相情感障碍患者(n = 1720)的内科疾病发病率,并根据终生内科疾病负担来检查双相情感障碍的临床病程。方法在英国招募的参与者被问及20种内科疾病的终生发生情况,使用神经精神病学临床评估表(SCAN)进行访谈,并根据DSM-IV标准进行诊断。结果我们发现双相样本中几种医学疾病的发生率显着增加。高疾病负担与焦虑症史,快速的自行车情绪发作,自杀企图和典型的急性发作情绪发作有关。结论双相情感障碍与高发病率有关。服务需要考虑这种合并症,以改善躁郁症患者的预后,并在研究情感性疾病病因的研究中,共享的生物途径可能在其中发挥作用。

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