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首页> 外文期刊>The British journal of psychiatry : >Tapering off long-term benzodiazepine use with or without group cognitive–behavioural therapy: three-condition, randomised controlled trial
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Tapering off long-term benzodiazepine use with or without group cognitive–behavioural therapy: three-condition, randomised controlled trial

机译：逐渐减少长期使用苯二氮卓类药物的集体或非集体认知治疗：三条件，随机对照试验

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Background Benzodiazepine withdrawal programmes have never been experimentally compared with a nonintervention control condition. Aims To evaluate the efficacy and feasibility of tapering off long-term benzodiazepine use in general practice, and to evaluate the value of additional group cognitivea€“behavioural therapy (CBT). Method A 3-month randomised, 3-month controlled trial was conducted in which 180 people attempting to discontinue long-term benzodiazepine use were assigned to tapering off plus group CBT, tapering off alone or usual care. Results Tapering off led to a significantly higher proportion of successful discontinuations than usual care (62% ??. 21%). Adding group CBT did not increase the success rate (58% v . 62%).Neither successful discontinuation nor intervention type affected psychological functioning. Both tapering strategies showed good feasibilityin general practice. Conclusions Tapering off is a feasible and effective way of discontinuing long-term benzodiazepine use in general practice.The addition of group CBT is of limited value.
机译：背景从未将苯二氮卓戒断方案与非干预性对照条件进行过实验比较。目的是评估逐渐减少长期使用苯二氮卓类药物的有效性和可行性，并评估其他集体认知行为疗法（CBT）的价值。方法进行了为期3个月，3个月的随机对照试验，其中180名试图中止长期使用苯二氮卓类药物的人被分配为逐渐减量加CBT组，逐渐减量为单独或常规护理。结果逐渐减少导致成功停药的比例显着高于常规护理（62％？。21％）。加入CBT组并没有增加成功率（58％对62％）。成功的中止治疗和干预类型都不会影响心理功能。两种渐缩策略在一般实践中均显示出良好的可行性。结论逐渐减量是中止长期停用苯二氮卓类药物的可行而有效的方法。CBT组的添加价值有限。

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