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Comorbid non-alcohol substance misuse among people with schizophrenia

机译:精神分裂症患者中非酒精类药物共混滥用

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Background Few epidemiological studies have assessed the extent and nature of comorbid non-alcohol substance misuse in people with schizophrenia in the community in the UK. Aims To study the extent and nature of comorbid non-alcohol substance misuse in people with schizophrenia in central London. Method Subjects were identified in an epidemiological census survey of South Westminster. Standardised assessment of each subject included demographic data, ratings of mental state and movement disorder and questioning about drug and alcohol misuse. Results Individuals with schizophrenia or related psychoses were identified ( n =352) and 57 (16%) reported a lifetime history of non-alcohol substance misuse. Age and gender were the main variables relevant to the extent and pattern of misuse. Self-reported non-alcohol substance misuse showed no significant relationship with a range of outcome measures. Conclusions The high proportion of subjects reporting non-alcohol substance misuse is comparable with figures from the USA. The reports of lifetime misuse most commonly referred to cannabis, psychostimulants, LSD, opiates and anticholinergics. Misuse was concentrated in those younger than 36 years and was reported more often by males.
机译:背景技术很少有流行病学研究评估了英国社区精神分裂症患者共病的非酒精药物滥用的程度和性质。目的研究在伦敦市中心患有精神分裂症的人共病的非酒精类药物滥用的程度和性质。方法在South Westminster的一次流行病学普查中确定受试者。对每个受试者的标准化评估包括人口统计学数据,精神状态和运动障碍的等级以及有关滥用药物和酒精的问题。结果鉴定出患有精神分裂症或相关精神病的个体(n = 352),其中57人(16%)报告了一生中无酒精滥用的病史。年龄和性别是与滥用程度和方式有关的主要变量。自我报告的非酒精类药物滥用与一系列结果指标没有显着关系。结论报告非酒精类药物滥用的受试者比例很高,可与美国的数字相媲美。关于终身滥用的报告最常涉及大麻,精神兴奋剂,LSD,鸦片和抗胆碱能药物。滥用现象主要集中在36岁以下的人群中,男性的滥用率更高。

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