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首页> 外文期刊>The British journal of psychiatry : >Tayside—Fife clinical trial of cognitive—behavioural therapy for medication-resistant psychotic symptoms
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Tayside—Fife clinical trial of cognitive—behavioural therapy for medication-resistant psychotic symptoms

机译:Tayside-Fife认知-行为疗法治疗抗药性精神病性症状的临床试验

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Background Evidence for the efficacy of cognitivea€”behavioural therapy for schizophrenia is promising but evidence for clinical effectiveness is limited. Aims To test the effectiveness of cognitivea€”behavioural therapy delivered by clinical nurse specialists in routine practice. Method Of 274 referrals, 66 were allocated randomly to 9 months of treatment as usual (TAU), cognitivea€”behavioural therapy plus TAU (CBT) or supportive psychotherapy plus TAU (SPT) and followed up for 3 months. Results Treatment effects were modest but the CBT condition gave significantly greater improvement in overall symptom severity than the SPT or TAU conditions combined ( F (1,53)=4.14; P =0.05). Both the CBT and SPT conditions combined gave significantly greater improvement in severity of delusions than did the TAU condition ( F (1,53)=4.83; P =0.03). Clinically significant improvements were achieved by 7/21 in the CBT condition (33%), 3/19 in the SPT condition (16%) and 2/17 in the TAU condition (12%). Conclusions Cognitivea€”behavioural therapy delivered by clinical nurse specialists is a helpful adjunct to routine care for some people with chronic psychosis.
机译:背景:精神分裂症认知行为疗法疗效的证据是有希望的,但临床有效性的证据有限。目的测试临床护士专家在常规实践中提供的认知行为疗法的有效性。方法在274例转诊中,有66例被随机分配到9个月的常规治疗(TAU),认知行为治疗加TAU(CBT)或支持性心理治疗加TAU(SPT),并随访3个月。结果治疗效果不明显,但是CBT病情比SPT或TAU病情综合症状的严重程度明显改善(F(1,53)= 4.14; P = 0.05)。与TAU条件相比,CBT和SPT条件的结合对妄想严重性的改善显着更大(F(1,53)= 4.83; P = 0.03)。在CBT情况下(33%),SPT情况下的3/19(16%)和TAU情况下的2/17(12%),临床上取得了显着改善。结论临床护士专家提供的认知行为疗法是一些慢性精神病患者常规护理的有用辅助手段。

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