• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The British journal of psychiatry : >Sexual dysfunction in people with prodromal or first-episode psychosis
【24h】

Sexual dysfunction in people with prodromal or first-episode psychosis

机译：前驱性或首发性精神病患者的性功能障碍

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background Sexual dysfunction is common in psychotic disorder but it is not clear whether it is intrinsic to the development of the illness or secondary to other factors. Aims To compare sexual function in people at ultra-high risk (UHR) of a psychotic disorder, patients with first-episode psychosis predominantly taking antipsychotic drugs and healthy volunteers. Method Sexual function was assessed in a UHR group ( n = 31), a group with first-episode psychosis ( n = 37) and a matched control group of healthy volunteers ( n = 56) using the Sexual Function Questionnaire. Results There was a significant effect of group on sexual function ( P 0.001). Sexual dysfunction was evident in 50% of the UHR group, 65% of first-episode patients and 21% of controls. Within the UHR group, sexual dysfunction was more marked in those who subsequently developed psychosis than in those who did not. Across all groups the severity of sexual dysfunction was correlated with the severity of psychotic symptoms ( P 0.001). Within the first-episode group there was no significant difference in sexual dysfunction between patients taking prolactin-raising v. prolactin-sparing antipsychotics. Conclusions Sexual dysfunction is present prior to onset of psychosis, suggesting it is intrinsic to the development of illness unlikely to be related to the prolactin-raising properties of antipsychotic medication.
机译：背景技术性功能障碍在精神病性疾病中很常见，但尚不清楚它是疾病发展的内在因素还是其他因素的继发因素。目的为了比较精神病性疾病的超高危人群（UHR）的性功能，首次发作的精神病患者主要服用抗精神病药物和健康志愿者。方法使用性功能问卷，在UHR组（n = 31），首发精神病组（n = 37）和健康志愿者的配对对照组（n = 56）中评估性功能。结果小组对性功能有显着影响（P <0.001）。 UHR组中有50％，首发患者中有65％和对照组中有21％患有性功能障碍。在UHR组中，后来患有精神病的人比没有精神病的人更明显地表现出性功能障碍。在所有组中，性功能障碍的严重程度与精神病症状的严重程度相关（P <0.001）。在首发组中，服用催乳素的患者与保留催乳素的抗精神病药患者之间的性功能障碍无显着差异。结论性功能障碍在精神病发作之前就已存在，这表明它是疾病发展的内在原因，与抗精神病药的催乳素特性无关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号