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首页> 外文期刊>The British journal of psychiatry : >Cognitive–behavioural therapy for severe and recurrent bipolar disorders
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Cognitive–behavioural therapy for severe and recurrent bipolar disorders

机译：严重和复发性双相情感障碍的认知行为疗法

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Background Efficacy trials suggest that structured psychological therapies may significantly reduce recurrence rates of major mood episodes in individuals with bipolar disorders. Aims To compare the effectiveness of treatment as usual with an additional 22 sessions of cognitivea€“behavioural therapy (CBT). Method We undertook a multicentre, pragmatic, randomised controlled treatment trial ( n =253). Patients were assessed every 8 weeks for18 months. Results More than half of the patients had a recurrence by 18 months, with no significant differences between groups (hazard ratio=1.05; 95% CI 0.74a€“1.50). Post hoc analysis demonstrated a significant interaction ( P =0.04) such that adjunctive CBT was significantly more effective than treatment as usual in those with fewer than 12 previous episodes, but less effective in those with more episodes. Conclusions People with bipolar disorder and comparatively fewer previous mood episodes may benefit from CBT. However, such cases form the minority of those receiving mental healthcare.
机译：背景功效试验表明，结构性心理疗法可能会显着降低躁郁症患者主要情绪发作的复发率。目的比较常规治疗与另外22次认知行为治疗（CBT）的疗效。方法我们进行了一项多中心，实用，随机对照治疗试验（n = 253）。患者每8周评估18个月。结果超过一半的患者在18个月时复发，各组之间无显着差异（危险比= 1.05; 95％CI 0.74a-1.50）。事后分析显示，二者之间存在显着的相互作用（P = 0.04），因此对于前发作次数少于12次的患者，辅助性CBT比通常的治疗显着有效，而对于发作次数较多的患者，CBT的疗效较差。结论双相情感障碍和以前情绪发作相对较少的人可能会受益于CBT。但是，这种情况在接受精神保健的患者中占少数。

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