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首页> 外文期刊>The British journal of psychiatry : >Cognitive-behavioural therapy for severe and recurrent bipolar disorders: randomised controlled trial.
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Cognitive-behavioural therapy for severe and recurrent bipolar disorders: randomised controlled trial.

机译：严重和复发性双相情感障碍的认知行为疗法：随机对照试验。

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BACKGROUND: Efficacy trials suggest that structured psychological therapies may significantly reduce recurrence rates of major mood episodes in individuals with bipolar disorders. AIMS: To compare the effectiveness of treatment as usual with an additional 22 sessions of cognitive-behavioural therapy (CBT). METHOD: We undertook a multicentre, pragmatic, randomised controlled treatment trial (n=253). Patients were assessed every 8 weeks for 18 months. RESULTS: More than half of the patients had a recurrence by 18 months, with no significant differences between groups (hazard ratio=1.05; 95% CI 0.74-1.50). Post hoc analysis demonstrated a significant interaction (P=0.04) such that adjunctive CBT was significantly more effective than treatment as usual in those with fewer than 12 previous episodes, but less effective in those with more episodes. CONCLUSIONS: People with bipolar disorder and comparatively fewer previous mood episodes may benefit from CBT. However, such cases form the minority of those receiving mental healthcare.
机译：背景：功效试验表明，结构性心理疗法可能会大大降低躁郁症患者主要情绪发作的复发率。目的：将常规治疗与另外22次认知行为治疗（CBT）的疗效进行比较。方法：我们进行了一项多中心，实用，随机对照治疗试验（n = 253）。每8周评估一次患者，持续18个月。结果：超过一半的患者在18个月前复发，各组之间无显着差异（危险比= 1.05; 95％CI 0.74-1.50）。事后分析表明，显着的交互作用（P = 0.04），因此对于前发作次数少于12次的患者，辅助性CBT比通常的治疗有效得多，而对于发作次数较多的患者，CBT的疗效较差。结论：双相情感障碍和以前情绪发作相对较少的人可能会受益于CBT。但是，这种情况在接受心理保健的患者中占很小比例。

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