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首页> 外文期刊>The British journal of psychiatry : >Effects of anxiety on the long-term course of depressive disorders
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Effects of anxiety on the long-term course of depressive disorders

机译：焦虑对抑郁症长期病程的影响

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Background It is well established that the presence of prominent anxiety within depressive episodes portends poorer outcomes. Important questions remain as to which anxiety features are important to outcome and how sustained their prognostic effects are over time. Aims To examine the relative prognostic importance of specific anxiety features and to determine whether their effects persist over decades and apply to both unipolar and bipolar conditions. Method Participants with unipolar (n = 476) or bipolar (n = 335) depressive disorders were intensively followed for a mean of 16.7 years (s.d. = 8.5). Results The number and severity of anxiety symptoms, but not the presence of pre-existing anxiety disorders, showed a robust and continuous relationship to the subsequent time spent in depressive episodes in both unipolar and bipolar depressive disorder. The strength of this relationship changed little over five successive 5-year periods. Conclusions The severity of current anxiety symptoms within depressive episodes correlates strongly with the persistence of subsequent depressive symptoms and this relationship is stable over decades.
机译：背景众所周知，抑郁发作中明显的焦虑预示着较差的预后。关于哪些焦虑症特征对结局很重要以及其预后效果随着时间的持续如何仍存在重要问题。目的探讨特定焦虑特征的相对预后重要性，并确定其影响是否持续数十年并适用于单相和双相疾病。方法对患有单相（n = 476）或双相（n = 335）抑郁症的参与者进行强化随访，平均时间为16.7年（标准误= 8.5）。结果焦虑症状的数量和严重程度，而不是先前存在的焦虑症的存在，与随后在单相和双相抑郁症中抑郁发作所花费的时间表现出稳健而持续的关系。在连续五个五年期间，这种关系的强度变化不大。结论抑郁发作中当前焦虑症状的严重程度与随后抑郁症状的持续存在密切相关，并且这种关系在数十年内是稳定的。

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