首页> 外国专利> compound of formula (i), or a salt thereof; composition of witania somnifera (ws) extract; pharmaceutical or nutraceutical composition; method of producing a composition of witania somnifera (ws) extract; method of producing a compound of formula (i); method of treating or preventing a dementia-related disorder in an individual; and method of treating or preventing an anxiety disorder or a depressive disorder in an individual

compound of formula (i), or a salt thereof; composition of witania somnifera (ws) extract; pharmaceutical or nutraceutical composition; method of producing a composition of witania somnifera (ws) extract; method of producing a compound of formula (i); method of treating or preventing a dementia-related disorder in an individual; and method of treating or preventing an anxiety disorder or a depressive disorder in an individual

机译：式（i）的化合物或其盐;茄子提取物的成分;药物或营养保健品组合物;一种用于生产茄子的提取物的方法。制备式（i）化合物的方法;治疗或预防个体与痴呆症相关的疾病的方法;或治疗个体的焦虑症或抑郁症的方法和方法

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a compound compound of formula (i), or a salt thereof; composition of witania somnifera (ws) extract; pharmaceutical or nutraceutical composition; method of producing a composition of witania somnifera (ws) extract; method of producing a compound of formula (i); method of treating or preventing a dementia-related disorder in an individual; and method of treating or preventing an anxiety disorder or a depressive disorder in an individual is an isolated and purified group of indolealkylamino-withasteroides conjugates of withania somnifera. A synthetic method of producing an indolealkylamino-withasteroid compound is provided. the in vitro inhibitory activity of acetyl cholinesterase and methods for treating dementia and dementia-related disorders such as alzheimer's disease, and anxiety and depressive disorders in mammals are demonstrated with such compositions of the invention. 1/1

机译：式（i）的化合物或其盐;茄子提取物的成分;药物或营养保健品组合物;一种用于生产茄子的提取物的方法。制备式（i）化合物的方法;治疗或预防个体与痴呆症相关的疾病的方法;治疗或预防个体的焦虑症或抑郁症的方法和方法是茄with的吲哚烷基氨基-withasteroides缀合物的分离和纯化基团。提供了一种制备吲哚烷基氨基-withasteroid化合物的合成方法。用本发明的此类组合物证明了乙酰胆碱酯酶的体外抑制活性以及治疗痴呆和痴呆相关疾病例如阿尔茨海默氏病以及哺乳动物的焦虑和抑郁症的方法。 1/1

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公开/公告号BR112014010868A8

专利类型
公开/公告日2017-06-20

原文格式PDF
申请/专利权人 NATREON INC.;
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申请/专利号BR20141110868
发明设计人 MURUGANANDAM VEERARAGAVAN;SANYASI R. KALIDINDI;SHIBNATH CHOSAL;
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申请日2012-11-06
分类号C07K16;
国家 BR
入库时间 2022-08-21 13:40:35

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