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首页> 外文期刊>The British journal of psychiatry : >Lifetime panic-depression comorbidity in the National Comorbidity Survey
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Lifetime panic-depression comorbidity in the National Comorbidity Survey

机译：全国性合并症调查中的终生恐慌-抑郁合并症

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Background Most prior studies of panic-depression comorbidity have been limited methodologically by use of small clinical samples and incomplete analyses.[a€?][1] Aims General population data were used to study the association of lifetime and recent (12 months) panic-depression comorbidity with symptom severity, impairment, course and help-seeking in the National Comorbidity Survey (NCS). Method The NCS is a nationally representative survey of the prevalences and correlates of major DSM-III-R disorders in the US household population. Results Strong lifetime and current comorbidity were found between panic and depression. Comorbidity was associated with greater symptom severity, persistence, role impairment, suicidality and help-seeking, with many findings persisting after controlling for additional comorbid diagnoses. Findings did not differ according to which disorder was chronologically primary. Conclusions Both lifetime and current panic-depression comorbidity are markers for more severe, persistent and disabling illness. Neither additional comorbid diagnoses nor the primary-secondary distinction were important moderators of these associations. [1]: #fn-1
机译：背景以往大多数恐慌抑郁合并症的研究都通过使用少量临床样本和不完整的分析进行了方法学限制。[a] [1]目的使用一般人群数据来研究寿命与近期（12个月）恐慌的相关性抑郁症合并症的症状严重程度，损害，病程和寻求帮助的情况在全国合并症调查（NCS）中进行。方法NCS是一项针对美国家庭人口中主要DSM-III-R疾病患病率和相关性的全国代表性调查。结果惊恐和抑郁之间有很强的寿命和当前合并症。合并症与更大的症状严重性，持续性，角色障碍，自杀倾向和寻求帮助有关，在控制了其他合并症诊断后，许多发现仍然存在。根据哪种疾病在时间上是主要的，研究结果没有差异。结论终生和当前的恐慌抑郁合并症都是更严重，持续和致残性疾病的标志。附加的合并症诊断和初级-次级诊断都不是这些协会的重要主持人。 [1]：＃fn-1

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