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首页> 外文期刊>The British journal of psychiatry : >Prepsychotic phase of schizophrenia and related disorders: recent progress and future opportunities
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Prepsychotic phase of schizophrenia and related disorders: recent progress and future opportunities

机译：精神分裂症和相关疾病的精神病前期：最近的进展和未来的机会

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Background Clinical and research focus has recently shifted from established psychotic disorders to first-episode psychosis and the prepsychotic phase of illness. Aims To describe the principles, progress and dilemmas associated with the prospective detection, engagement and treatment of young people at risk of developing a psychotic disorder. Method Strategies to identify young people at heightened risk of a psychotic disorder are described. Preventive interventions and results of their evaluation are provided. Results Well-validated criteria for identifying young people at heightened risk of psychosis have been developed, evidence of the efficacy of various psychological and pharmacological interventions in preventing progression has accumulated and progress towards the identification of clinical and neurobiological predictors of transition to acute psychosis has been made. Conclusions The detection, monitoring and treatment of young people in the prepsychotic phase is a growth area in psychiatry. The ethical considerations about treatment options, treatment of minors and provision of information about risk status must be treated with sensitivity if the potential benefit to many young people and their families is to be realised.
机译：背景技术最近的临床和研究重点已从既定的精神病转移到首发精神病和疾病的精神病前期。目的描述与有可能患精神病的年轻人的预期检测，参与和治疗相关的原理，进展和困境。方法策略描述了识别年轻人的精神病的高风险。提供了预防性干预措施及其评估结果。结果已开发出有效的鉴定标准，用于识别患有高度精神病的年轻人，已经积累了各种心理和药物干预措施预防进展的证据，并且在确定向急性精神病过渡的临床和神经生物学预测指标方面取得了进展。制作。结论精神病前期青年的检测，监测和治疗是精神病学的增长领域。如果要实现对许多年轻人及其家庭的潜在利益，必须谨慎对待有关治疗选择，未成年人的治疗以及提供有关风险状况的信息的道德考虑。

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