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Pneumococcal vaccination in older persons: where are we today?

机译:老年人肺炎球菌疫苗接种:我们今天在哪里?

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Disease due to Streptococcus pneumoniae , the pneumococcus, remains a major source of illness in older persons. Globally, it remains the most important pathogen in respiratory infection deaths.Conjugated pneumococcal vaccines are used extensively in national pediatric programs, whereas a polysaccharide vaccine is used in all age groups, but mainly in the elderly and for high-risk groups.Recent data from the Netherlands led to the licensing in many countries of conjugated pneumococcal vaccines for older persons. There are substantial differences in recommendations from various national immunization technical advisory groups, which owe at least as much to differing assessments of available studies as to differences in local epidemiology.This review examines those differences and proposes a way forward.
机译:肺炎链球菌肺炎链球菌引起的疾病仍然是老年人的主要疾病来源。在全球范围内,它仍然是呼吸道感染死亡中最重要的病原体。结合的肺炎球菌疫苗已在国家儿科计划中广泛使用,而多糖疫苗已在所有年龄段使用,但主要在老年人和高危人群中使用。荷兰在许多国家获得了针对老年人的结合型肺炎球菌疫苗的许可。各个国家免疫技术咨询小组的建议之间存在实质性差异,这至少应归功于对现有研究的不同评估以及当地流行病学的差异,本文对这些差异进行了研究并提出了前进的方向。

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