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首页> 外文期刊>The Internet Journal of Pharmacology >Diabetes :A Paradigm and its Prevention
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Diabetes :A Paradigm and its Prevention

机译：糖尿病：范式及其预防

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Diabetes is a progressive disease with acute and chronic morbidities and high mortality. At present there are 171 million diabetic patients in the world with India accounting for 31.7 million. Prevalence in India is expected to increase to 79.4 million by the year 2030[1]. Approximately 85 -90% of these people have type 2 diabetes mellitus. The illness is best managed by combining patient education and long-term medical care to prevent or to reduce the risk of long-term complications. Diabetes is associated with serious health consequences. It has been the leading cause of coronary heart disease (CHD), stroke and chronic renal failure, hypertension, atherosclerosis, endothelial dysfunction. Management of diabetes is intricate and requires many issues be addressed beyond glycemic control alone. According to American Diabetic Associtaion (2002), the cost related to diabetes for hospitalization and complications was $132 billion [3] and formed 34% of the medical budget. A large body of evidence exists that supports a range of interventions to improve diabetes outcomes. The studies like UKPDS [4-6], DCCT [7, 8] and Kumamoto [9] have shown a significant decrease in cost and complications with an intensive glycemic and blood pressure control.Diabetes is a chronic disease treated for long with goal of ‘secondary prevention’ but failed to provide complete prevention of complications. The rising prevalence of the disease and cost of treatment will probably offset its benefits to the community. A shift in paradigm from secondary prevention to primary prevention of diabetes is the need of the hour but has been neglected or as has been underachieved in routine clinical practice.
机译：糖尿病是一种具有急性和慢性发病率和高死亡率的进行性疾病。目前，世界上有1.71亿糖尿病患者，印度占3170万。到2030年，印度的患病率预计将增加到7940万[1]。这些人中约有85 -90％患有2型糖尿病。通过结合患者教育和长期医疗保健，可以预防或减少长期并发症的风险，从而最好地控制疾病。糖尿病与严重的健康后果有关。它一直是冠心病（CHD），中风和慢性肾功能衰竭，高血压，动脉粥样硬化，内皮功能障碍的主要原因。糖尿病的治疗错综复杂，不仅需要控制血糖，还需要解决许多问题。根据美国糖尿病协会（2002年），与糖尿病相关的住院和并发症费用为1,320亿美元[3]，占医疗预算的34％。存在大量证据支持一系列改善糖尿病预后的干预措施。 UKPDS [4-6]，DCCT [7，8]和熊本[9]等研究显示，通过强化血糖和血压控制，费用和并发症显着减少。糖尿病是一种长期治疗的慢性病，​​目标是“二级预防”但未能完全预防并发症。这种疾病的流行和治疗费用的上升可能会抵消其对社区的好处。糖尿病需要从二级预防向一级预防的转变，这是一个小时的需求，但已被忽视，或者在常规临床实践中未能实现。

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