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Genetically manipulated mice models as research tool

机译:转基因小鼠模型作为研究工具

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Genetically modified mouse models have emerged as an excellent approach to provide insight into gene regulation, development, pathogenesis, and the treatment of disease.Transgenic models are the biological tools that aid target discovery, validation, and production of therapeutic proteins. Despite several theoretical and technical challenges in generation of knockout models, transgenic technology holds great potential in many fields including medicine, industry. This short review covers briefly the methods used to produce transgenic mice and the importance of these genetically modified animals in biomedical research.
机译:转基因小鼠模型已经成为一种了解基因调控,发育,发病机理和疾病治疗的极佳方法。转基因模型是有助于靶标发现,验证和生产治疗性蛋白质的生物学工具。尽管产生基因敲除模型在理论和技术上都存在挑战,但转基因技术在包括医学,工业在内的许多领域仍具有巨大潜力。这篇简短的综述简要介绍了用于生产转基因小鼠的方法以及这些转基因动物在生物医学研究中的重要性。

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