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Lacune and lacunar infarct: A history of the concept and modern use

机译:腔隙和腔隙性梗塞:概念和现代用法的历史

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Lacune was a term first used in the European literature in the mid 19th century but was little used in English language medical literature until the publications of Charles Miller Fisher in the 1960's. The lacunar hypothesis is controversial and the terminology is best reserved for the pathological lesion. New clinical classifications of stroke such as that proposed in the TOAST study have demonstrated a high interphysician agreement rate and are widely employed.
机译:Lacune是19世纪中叶首先在欧洲文学中使用的术语,但直到1960年代Charles Miller Fisher的出版物才在英语医学文献中很少使用。腔隙假说是有争议的,术语最适合病理病变。新的中风临床分类法(如TOAST研究中提出的分类法)已显示出较高的医师间认同率,并被广泛采用。

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