...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Internet Journal of Orthopedic Surgery >Impact Of HIV Kit On HIV Testing: Observations From A Nigerian Teaching Hospital
【24h】

Impact Of HIV Kit On HIV Testing: Observations From A Nigerian Teaching Hospital

机译：艾滋病毒试剂盒对艾滋病毒检测的影响：尼日利亚教学医院的观察

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Sir,Laboratory testing of patients for the Human Immunodeficiency Virus (HIV) infection is an important procedure that has a substantial impact on HIV diagnosis. As the knowledge of HIV infection is increasing, so also is the complexity of laboratory tests for its detection. The first HIV antibodies detection technique was licensed in 1985 by the Food and Drug Administration (FDA) in America and since then several kits have been produced and introduced into the world markets (1). When HIV antibodies technique was introduced many years ago, the World Health Organization (WHO) recommended that the double ELISA technique be adopted by developing countries before a patient can be said to be positive for HIV infection (2, 3) .This was to avoid the false positive results often associated with these technologies. (First and second generation ELISA kits). As time went on, the government of Nigeria introduced immunoconfirmatory technique for better reliability of results.The Aminu Kano Teaching Hospital, Kano, Nigeria introduced the immunoconfirmatory technology in May, 1998. Prior to this period, the double ELISA technology was used. We collated and compared laboratory test results and records for a period of seven months before and after the introduction of immunoconfirmatory technology. We observed that the cost per test increased from two hundred and fifty naira (2 dollars) to five hundred naira (4 dollars) following the introduction of immunoconfirmatory technology. There was however a reduction in the number of patients from 289 to 258 over the two periods. The prevalence of reactive HIV antibodies however decreased from 43.6% to 36.8%.The drop in the number of patients who came for HIV antibody testing may be attributable to the doubling of the unit cost of HIV test from N250 naira (2 dollars) to five hundred naira (4 dollars). We also noted that the second period witnessed a reduction in the number of positive samples from a prevalence of 43.6% to 36.8%. It is possible that false positive results may have been recorded initially before the introduction of immunoconfirmatory tests. The drop in the number of patients who turned up for HIV testing may also contribute to the fall in prevalence in the latter period.In conclusion therefore, even though patients may have paid more for HIV testing following the introduction of immunoconfirmatory technology, it is important to note that this technology has significantly improved the reliability of HIV test results, with better assurance and more confidence on HIV diagnosis. Health care providers and authorities in Nigeria and elsewhere in Africa are encouraged to introduce HIV immunoconfirmatory technology in their respective centers.
机译：主席先生，对患者进行人体免疫缺陷病毒（HIV）感染的实验室测试是一项重要程序，对HIV诊断产生重大影响。随着对HIV感染知识的增加，检测它的实验室测试的复杂性也在增加。最早的HIV抗体检测技术于1985年获得美国食品药品监督管理局（FDA）的许可，此后，已经生产了数种试剂盒并将其引入世界市场（1）。多年前引入HIV抗体技术时，世界卫生组织（WHO）建议发展中国家采用双重ELISA技术，然后才能说患者对HIV感染呈阳性（2，3）。这些技术通常会带来假阳性结果。 （第一代和第二代ELISA试剂盒）。随着时间的流逝，尼日利亚政府引入了免疫确认技术以提高结果的可靠性。尼日利亚卡诺的Aminu Kano教学医院于1998年5月引入了免疫确认技术。在此之前，曾使用双重ELISA技术。在整理免疫确认技术前后，我们整理并比较了七个月的实验室测试结果和记录。我们观察到，在引入免疫确证技术后，每次测试的费用从250奈拉（2美元）增加到500奈拉（4美元）。但是，在这两个时期内，患者人数从289人减少到258人。但是，反应性HIV抗体的患病率从43.6％下降到36.8％。接受HIV抗体检测的患者人数下降可能是由于HIV检测的单位成本从N250奈拉（2美元）翻了一番一百奈拉（4美元）。我们还注意到，第二个时期的阳性样本数量从43.6％下降到36.8％。在引入免疫确认试验之前，最初可能已经记录了假阳性结果。接受HIV检测的患者数量下降也可能导致后期患病率下降。因此，总的来说，即使在引入免疫确诊技术后患者可能为HIV检测支付了更多费用，这一点也很重要需要注意的是，这项技术显着提高了HIV检测结果的可靠性，并具有更好的保证和对HIV诊断的信心。鼓励尼日利亚和非洲其他地区的医疗保健提供者和当局在各自的中心引入HIV免疫确认技术。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号