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首页> 外文期刊>The Journal of Musculoskeletal and Neuronal Interactions >Bone health measured using quantitative ultrasonography in adult males with muscular dystrophy
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Bone health measured using quantitative ultrasonography in adult males with muscular dystrophy

机译：使用定量超声检查对成年男性肌营养不良症的骨健康状况

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Objectives: To compare muscle and bone health markers in adult males (aged 20-59 yrs) with and without muscular dystrophy (MD). Methods: Participants included 11 Fascioscapulohumeral (FSH), 11 Becker's (Be), 9 limb girdle (LG), 11 Duchenne (DMD), and 14 non-dystrophic controls (CTRL). Physical activity was assessed using Bone (BPAQ) and disabil- ity specific (PASIPD) questionnaires. Bone QUS provided T- and Z scores from the Distal Radius (DR) and Mid-shaft tibia (MST). Tibialis anterior cross sectional area (TA ACSA ) was measured using B-mode ultrasound. Grip strength was measured in all but DMD. Results: Physical activity was lower in DMD, FSH and BeMD than CTRL (P<0.05), and lower in DMD than other MDs (P<0.01). T and Z scores were lower in DMD and Be than CTRL (DR, P<0.05); and lower in DMD than CTRL, LG, and FSH (MST, P<0.01). TA ACSA and grip strength was 35-59% and 50-58% smaller in MD than CTRL, respectively (P<0.01). Within MD, BPAQ correlated with bone QUS measures (r=0.42-0.38, P<0.01). PASIPD correlated with grip strength (r=0.65, P<0.01) and TA ACSA (r=0.46, P<0.01). Conclusion: Muscle size, strength, and bone health was lower in adult males with MD compared to adult males without MD, the extent of this is partially determined by physical activity.
机译：目的：比较患有和不患有肌营养不良（MD）的成年男性（20-59岁）的肌肉和骨骼健康指标。方法：参与者包括11例筋膜肱骨（FSH），11例贝克（Be），9根腰带（LG），11例杜氏（DMD）和14例非营养不良对照（CTRL）。使用骨骼（BPAQ）和特定于残障人士（PASIPD）的问卷来评估身体活动。骨QUS提​​供了远端半径（DR）和中轴胫骨（MST）的T和Z评分。使用B型超声测量胫骨前横截面积（TA ACSA）。除DMD外，其余所有均测量了握力。结果：DMD，FSH和BeMD的体力活动低于CTRL（P <0.05），而DMD的体力活动低于其他MD（P <0.01）。 DMD和Be中的T和Z得分低于CTRL（DR，P <0.05）;在DMD中低于CTRL，LG和FSH（MST，P <0.01）。 TA ACSA和握力在MD上分别比CTRL减小35-59％和50-58％（P <0.01）。在MD内，BPAQ与骨骼QUS量度相关（r = 0.42-0.38，P <0.01）。 PASIPD与握力（r = 0.65，P <0.01）和TA ACSA（r = 0.46，P <0.01）相关。结论：与没有MD的成年男性相比，患有MD的成年男性的肌肉大小，强度和骨骼健康状况较低，其程度部分取决于体育锻炼。

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