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首页> 外文期刊>The Open Anesthesia Journal >The use of “High Dose” Dexmedetomidine in a Patient with CriticalTracheal Stenosis and Anterior Mediastinal Mass
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The use of “High Dose” Dexmedetomidine in a Patient with CriticalTracheal Stenosis and Anterior Mediastinal Mass

机译：严重气管狭窄和纵隔前肿块患者中“大剂量”右美托咪定的使用

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摘要

The anterior medial mass patient continues to offer great challenges for the anesthesiologist. As such, newerand safer methods of providing anesthetic care are continually being sought. To this end, there is a growing body ofevidence that may suggest that higher than Food and Drug Administration approved dosages of dexmedetomidine mayoffer another option in the arsenal of the anesthesiologist in this patient population.We recently cared for a middle aged male who presented with a large mediastinal mass, extrinsic compression criticaltracheal stenosis, superior vena cava syndrome, and massive supraclavicular lymphadenopathy, scheduled for trachealstent placement, biopsy, and diagnostic evaluation of the esophagus. After reviewing anesthetic options, we deemed thesafest technique available to us to be the use of a high dose dexmedetomidine based technique with continuous infusionrate of 2mcg/kg/hr. Spontaneous respirations were maintained throughout the case, with a stable heart rate and bloodpressure, and our patient tolerated the procedure without complications.
机译：前内侧肿块患者继续为麻醉医师带来巨大挑战。因此，一直在寻求提供麻醉护理的更新和更安全的方法。为此，越来越多的证据表明，高于美国食品药品管理局批准的右美托咪定剂量可能为该患者人群的麻醉师提供了另一种选择。纵隔肿大，外在压迫性气管狭窄，上腔静脉综合征和锁骨上淋巴结肿大，计划行气管放置，活检和食道诊断评估。在审查了麻醉选择之后，我们认为最安全的技术是使用基于大剂量右美托咪定的技术，连续输注2mcg / kg / hr。整个病例保持自发呼吸，心率和血压稳定，我们的患者耐受手术，无并发症。

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