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首页> 外文期刊>The Open Anesthesia Journal >Acquired-Hypernatraemia in the Intensive Care Units
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Acquired-Hypernatraemia in the Intensive Care Units

机译：重症监护室获得性高钠血症

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Objectives:Determine the incidence and predisposing factors of acquired-hypernatraemia in the intensive care units (ICU) and its impact on the outcome.Design:Observational cross-sectional study with prospective analysis. Setting: Surgical, medical and trauma intensive care units of National Hospital of Sri Lanka.Study Population:174 consecutive patients were included in this study.Definition:Hypernatraemia was defined as serum sodium concentration > 145 mmol/l. Results: 74 patients (42.5%) developed hypernatraemia after admission to the intensive care units. Incidence in medical, surgical and trauma ICUs were 47%, 48% and 31% respectively. Significantly lower incidence was reported in patients with trauma compared to the patients from the other two ICUs. High APACHE II (Acute Physiology and Chronic Health Evaluation) score, low GCS (Glasgow Coma Scale), organ dysfunction, transfusion of blood and blood products were associated with an increased incidence of hypernatraemia. Hypernatraemic patients had received significantly greater volume of intravenous fluids exceeding their daily fluid requirement. Compared to normonatraemic patients, hypernatraemic patients demonstrated a longer length of stay (LOS) in the ICU (mean 4.8 days versus 11 days, p < 0.001) and a higher ICU-mortality rate (15% versus 43%, p <0.001). Conclusions:Severity of the illness, inappropriate intravenous fluid therapy and blood transfusions contribute to the incidence of hypernatraemia in intensive care units. It is associated with increased risk of ICU-mortality and longer length of stay in the ICU.
机译：目的：确定重症监护病房（ICU）中获得性高钠血症的发生率，诱发因素及其对结局的影响。设计：前瞻性观察性横断面研究。地点：斯里兰卡国立医院的外科，医疗和创伤重症监护室。研究人群：本研究包括174名连续患者。定义：高钠血症定义为血清钠浓度> 145 mmol / l。结果：74名患者（42.5％）进入重症监护室后出现了高钠血症。内科，外科和创伤ICU的发生率分别为47％，48％和31％。与其他两个ICU的患者相比，创伤患者的发病率显着降低。高APACHE II（急性生理和慢性健康评估）评分，低GCS（格拉斯哥昏迷量表），器官功能障碍，输血和输血与高钠血症发生率增加相关。高钠血症患者接受的静脉输液量大大超过了他们的每日输液量。与正常人群相比，高钠血症患者在ICU的住院时间（LOS）更长（平均4.8天vs 11天，> 0.001），并且ICU死亡率更高（15％对比43％，p <0.001）。结论：疾病的严重程度，不适当的静脉输液治疗和输血导致重症监护病房的高钠血症发生率。它与ICU死亡风险增加以及在ICU中停留时间更长有关。

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