首页> 外文期刊>The Journal of Reproduction and Development >The Use of Embryonic Stem Cell Derived Bioactive Material as a New Protein Supplement for the In Vitro Culture of Bovine Embryos
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The Use of Embryonic Stem Cell Derived Bioactive Material as a New Protein Supplement for the In Vitro Culture of Bovine Embryos

机译:胚胎干细胞衍生的生物活性物质作为牛胚胎体外培养的新型蛋白质补充剂的用途

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Embryonic stem (ES) cells are expanded versions of the inner cell mass cells that compose the early mammalian blastocyst. Components derived from ES cells may contain various bioactive materials (BM) helpful for early preimplantation embryo growth. In this study, we examined the effect of human ES cell derived BM (hES-BM) on in vitro culture of bovine embryos. When bovine parthenogenetic day 2 embryos were cultured in 10% hES-BM, a significantly higher embryo development rate (44.3%) and increased cell numbers were observed relative to control medium containing 3 mg/ml BSA (19.5%; P
机译:胚胎干(ES)细胞是组成早期哺乳动物胚泡的内部细胞大规模细胞的扩展版本。来自ES细胞的成分可能包含有助于早期植入前胚胎生长的各种生物活性物质(BM)。在这项研究中,我们检查了人类ES细胞衍生的BM(hES-BM)对牛胚胎体外培养的影响。当在10%hES-BM中培养牛孤雌生殖第2天胚胎时,相对于含3 mg / ml BSA的对照培养基(19.5%; P

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