Development of Dry Powder Inhaler Containing Prothionamide-PLGA Nanoparticles Optimized Through Statistical Design: In-vivo Study

Debnath Sujit K.; Srinivasan Saisivam; Debnath Monalisha

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Development of Dry Powder Inhaler Containing Prothionamide-PLGA Nanoparticles Optimized Through Statistical Design: In-vivo Study

机译：通过统计设计优化的含有乙硫酰胺-PLGA纳米颗粒的干粉吸入器的开发：体内研究

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Objective:The objective of the present work was to formulate Prothionamide (PTH) nanoparticles using Poly lactic co-glycolic acid (PLGA), optimized by Box-Behnken Design and further modification to dry powder inhaler followed by in-vivo study.

机译：目的：本研究的目的是使用聚乳酸共乙醇酸（PLGA）配制Prothionamide（PTH）纳米颗粒，并通过Box-Behnken Design优化设计，然后进一步对干粉吸入器进行改性，然后进行体内研究。

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《The Open Nanomedicine Journal》 |2017年第1期|共11页
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Debnath Sujit K.; Srinivasan Saisivam; Debnath Monalisha;
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中图分类基础医学;
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1. Air classifier technology (ACT) in dry powder inhalation Part 3. Design and development of an air classifier family for the Novolizer multi-dose dry powder inhaler. [J] . de Boer AH, Hagedoorn P, Gjaltema D, International Journal of Pharmaceutics . 2006,第1a2期

机译：干粉吸入中的空气分类器技术（ACT）第3部分。用于Novolizer多剂量干粉吸入器的空气分类器系列的设计和开发。
2. Development of Budesonide Loaded Biopolymer Based Dry Powder Inhaler: Optimization,In VitroDeposition, and Cytotoxicity Study [J] . Ashwin J.Mali, Atmaram P.Pawar, Ravindra N.Purohit Journal of Pharmaceutics . 2014,第3期

机译：布地奈德负载生物聚合物基干粉吸入器的开发：优化，体外沉积和细胞毒性研究
3. Development of a high efficiency dry powder inhaler: Effects of capsule chamber design and inhaler surface modifications [J] . BeharaS.R.B., FarkasD.R., HindleM., Pharmaceutical research . 2014,第2期

机译：高效干粉吸入器的开发：胶囊室设计和吸入器表面改性的影响
4. COMPARISON OF THE APPLICATION OF A RISK-BASED APPROACH TO THE DESIGN OF AN EXTRACTABLES AND LEACHABLES PROGRAMME FOR THE STUDY OF A BIOPHARMACEUTICAL AND DRY POWDER INHALER PRODUCT [C] . Jason Creasey Rapra International Conference on Blowing Agents and Foaming Processes . 2011

机译：基于风险的方法在生物制药和干粉吸入器研究中应用基于风险的方法和脱色程序设计的比较
5. Advanced Design and Development of Novel Microparticulate/Nanoparticulate Dry Powder Inhalers for Targeted Treatment of Pulmonary Hypertension [D] . Acosta, Maria Fernanda. 2019

机译：新型微粒的先进设计和开发/纳米颗粒干粉吸入器针对肺动脉高压的靶向治疗
6. Development of Budesonide Loaded Biopolymer Based Dry Powder Inhaler: Optimization In Vitro Deposition and Cytotoxicity Study [O] . Ashwin J. Mali, Atmaram P. Pawar, Ravindra N. Purohit 2014

机译：基于布地奈德生物聚合物的干粉吸入器的开发：优化体外沉积和细胞毒性研究
7. Development of a Rational Design Space for Optimizing Mixing Conditions for Formation of Adhesive Mixtures for Dry-Powder Inhaler Formulations [O] . Saurabh Sarkar, Bruna Minatovicz, Kyrre Thalberg, 2017

机译：研制理性设计空间，用于优化形成干粉吸入器配方粘合剂混合物的混合条件

Development of Dry Powder Inhaler Containing Prothionamide-PLGA Nanoparticles Optimized Through Statistical Design: In-vivo Study

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