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首页> 外文期刊>The Open Complementary Medicine Journal >A Double Blinded- Randomized Clinical Study with 'Weighlevel', aCombination of Four Medicinal Plants Used in Traditional Greco-Araband Islamic Medicine
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A Double Blinded- Randomized Clinical Study with 'Weighlevel', aCombination of Four Medicinal Plants Used in Traditional Greco-Araband Islamic Medicine

机译：一项“双水平”双盲随机临床研究，将传统希腊-阿拉伯无伊斯兰教医学中使用的四种药用植物结合在一起

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Weighlevel, is a mixture of extract of leaves of Alchemilla vulgaris, Olea europea and Mentha longifolia L, aswell as seeds of Cuminum cyminum. These plants are used in traditional Greco-Arabic and Islamic medicine as well as inEuropean herbal medicine. Weighlevel has been recently found to be safe and effective in weight loss in preclinical invitro and in vivo studies, including a preliminary, uncontrolled human trial. Here we report the results of our randomized,double blinded, placebo controlled clinical study. The tests were carried out among 34 human volunteers. The test groupincluded 19 volunteers whereas the control group included 15 volunteers who consumed Weighlevel tablets or placebotablets 1 x 3 daily, respectively. All 34 subjects were asked to continue their usual diet, except for strictly limiting foodintake to 3 main meals per day without snacking, and to take one Weighlevel tablet or placebo tablet 30 minutes beforeeach meal. Five subjects were excluded (three from the test group and two from the control group) due to absence fromscheduled visits. Twenty-nine subjects were evaluated for efficacy and tolerability of Weighlevel every month for 3months. Weighlevel was well tolerated by all subjects and no side effects were reported. After 12 weeks, test subjects, onaverage, showed statistically significant weight loss and body mass index (BMI) reductions. Weight and BMI changes forthe placebo group were not statistically significant. Results indicate safety, tolerability, and efficacy of Weighlevel inweight loss.
机译：Weighlevel是寻常的炼金术，欧洲油橄榄和薄荷叶的提取物以及小茴香的种子的混合物。这些植物用于传统的希腊-阿拉伯和伊斯兰医学以及欧洲的草药中。最近，在临床前的体外和体内研究（包括一项未经控制的初步人体试验）中，称量体重可以安全有效地减轻体重。在这里，我们报告了我们的随机，双盲，安慰剂对照临床研究的结果。测试是在34位人类志愿者中进行的。测试组包括19名志愿者，而对照组包括15名每天分别服用Weighlevel片剂或可食用的1 x 3的志愿者。所有34名受试者均被要求继续日常饮食，除了严格限制每天进食3顿主餐且不吃零食，并在每次进餐前30分钟服用一枚Weighlevel片剂或安慰剂片剂。由于没有预定的探访，排除了五名受试者（测试组三名，对照组两名）。每月对29名受试者进行3个月的Weighlevel疗效和耐受性评估。所有受试者对体重水平的耐受性都很好，并且没有副作用的报道。 12周后，测试对象平均显示出统计学上显着的体重减轻和体重指数（BMI）降低。安慰剂组的体重和BMI变化无统计学意义。结果表明体重减轻体重的安全性，耐受性和功效。

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