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Immunity and Virulence in Bird-Parasite Interactions

机译:鸟寄生虫相互作用中的免疫力和毒力。

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The interaction between hosts and parasites is characterized by the evolution of reciproca adaptations aiming at reducing the cost of infection (from the host point of view) and to optimize host exploitation (from the parasite point of view). Within this co-evolutionary scenario, the immune system takes a central role. The immune system has evolved to fight off parasitic attacks. However, immune defences cannot be deployed without costs which set a limit to the protective effect of immunity. Moreover, immune defences impose strong selection pressures on the parasite and can favour the evolution of more virulent pathogen strains. In this article, we will discuss these different issues focusing on host-pathogen interactions involving birds and their parasites.
机译:宿主与寄生虫之间的相互作用的特征在于互惠适应的发展,旨在降低感染成本(从宿主的角度)并优化宿主的利用(从寄生虫的角度)。在这种共同进化的情况下,免疫系统起着核心作用。免疫系统已发展为抵御寄生虫攻击。但是,没有成本就无法部署免疫防御,而这限制了免疫的保护作用。此外,免疫防御会对寄生虫施加强大的选择压力,并可能促进更具毒性的病原体菌株的进化。在本文中,我们将讨论这些不同的问题,重点是涉及鸟类及其寄生虫的宿主-病原体相互作用。

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