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首页> 外文期刊>The Professional Medical Journal >CERVICAL DISEASES; To compare the efficacies of pap smear cytology, colposcopy and histopathology, in gynaecological diagnosis
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CERVICAL DISEASES; To compare the efficacies of pap smear cytology, colposcopy and histopathology, in gynaecological diagnosis

机译:宫颈疾病;比较宫颈涂片细胞学检查,阴道镜检查和组织病理学在妇科诊断中的功效

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Objectives: The aim of our study is to compare the efficacies of Pap smear cytology, colposcopy and histopathology, in diagnosis of cervical diseases. Study Design: Cross sectional cohort study. Period: One year from June 2013 to June 2014. Setting: Tertiary care hospital in Karachi, Pakistan. Method: The patient population n=145 consisted of women ranging from age 18 to 80 years old, who had come to the outpatient clinics for a variety of symptoms. Pap smear, colposcopy and histopathology was done for women who had symptoms like recurrent vaginal discharge, postcoital bleeding and other diseases of the cervix. Findings were noted on a proforma and all the patients signed a duly informed consent. Data was analyzed using SPSS version 23. Results: The mean age was 45 +/- 9 years (between 24 – 75 years), the parity was 5 +/- 4, normal colposcopy findings were found in n= 66 women, while abnormal findings were found in n=79 women. In the abnormal colposcopic finding group n=63 had abnormal histopathology (p<0.001) abnormal histopathology was found in n=11 women who had normal colposcopic findings (16.67% false negative), the calculated sensitivity and specificity of colposcopy was determined to be 86% and 79%. For pap smear abnormality was found in n= 49 patients, out of which n=29 had abnormal findings on histopathology as well. And for colposcopy and pap smear out of n= 78 patients who had abnormal colposcopic findings, abnormal pap smear was found in only n= 28 patients. And out of those who had normal colposcopy n= 67, n= 21 had abnormal pap smear (False positivity of 31.34%) similarly out of those who had normal pap smear n= 96, n= 44 had abnormal histopathology (false negativity of 45.83%). The calculated sensitivity and specificity of pap smear was 38.8% and 71.8% respectively. Conclusion: We have concluded that there is a strong correlation between findings of colposcopy and histopathological diagnosis, but when it comes to the diagnosis made by pap smear and colposcopy and pap smear and histopathology the correlation is weak and not consistent.
机译:目的:我们的研究目的是比较宫颈涂片细胞学检查,阴道镜检查和组织病理学检查在宫颈疾病诊断中的功效。研究设计:横断面队列研究。期间:2013年6月至2014年6月,为期一年。地点:巴基斯坦卡拉奇的三级医疗医院。方法:患者人群n = 145,包括年龄在18至80岁之间的女性,她们因各种症状前往门诊就诊。对症状如复发白带,性交后出血和其他宫颈疾病的妇女进行了子宫颈抹片检查,阴道镜检查和组织病理学检查。在形式上记录发现,所有患者均签署了知情同意书。数据使用SPSS 23版进行分析。结果:平均年龄为45 +/- 9岁(24至75岁之间),胎次为5 +/- 4,n例66例女性中阴道镜检查正常,而异常在n = 79名妇女中发现了这些发现。在阴道镜检查异常组中,n = 63的组织病理学异常(p <0.001),在n = 11名阴道镜检查结果正常的女性中发现了异常的组织病理学(假阴性为16.67%),确定的阴道镜检查的敏感性和特异性为86 %和79%。对于n = 49位患者,发现了宫颈涂片异常,其中n = 29位也具有组织病理学异常。对于阴道镜检查发现异常的n例78例患者中的阴道镜检查和巴氏涂片检查,只有n例28例患者发现了巴氏涂片异常。在阴道镜检查正常的患者中,n = 67,n = 21的宫颈涂片异常(假阳性率为31.34%),在阴道镜检查正常的n = 96中,n = 44的组织病理学异常(假阴性为45.83)。 %)。估计的子宫颈抹片检查的敏感性和特异性分别为38.8%和71.8%。结论:我们得出的结论是,阴道镜检查结果与组织病理学诊断之间存在很强的相关性,但就子宫颈抹片检查和阴道镜检查以及宫颈抹片涂片和组织病理学所做的诊断而言,相关性较弱且不一致。

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