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Bacterial and Hematological Findings in Infected Total Hip Arthroplasties in Norway Assessment of 278 Revisions Due to Infection in the Norwegian Arthroplasty Register

机译:挪威感染性全髋关节置换术的细菌学和血液学发现评估挪威置换术中因感染引起的278次修订

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Our aim was to assess the bacterial findings in infected total hip arthroplasties (THAs) in Norway. We also wanted to investigate the relationship between causal bacteria and hematological findings. Revisions reported to the Norwegian Arthroplasty Register (NAR) due to infection after total hip arthroplasty during the period 1993 through September 2007 were identified. One single observer visited ten representative hospitals where clinical history, preoperative blood samples and the bacterial findings of intraoperative samples were collected. Bacterial growth in two or more samples was found in 278 revisions, and thus included. The following bacteria were identified: Coagulase-negative staphylococci (CoNS) (41%), Staphylococcus aureus (S. aureus) (19%), streptococci (11%), polymicrobial infections (10%), enterococci (9%), Gram-negative bacteria (6%) and others (4%). CoNS were the most common bacteria throughout the period but in the acute postoperative infections (< 3 weeks) S. aureus was the most frequent bacterial finding. We found no change in the distribution of the bacterial groups over time. S. aureus appears correlated with a higher C-reactive protein value (CRP) (mean 140 (95% Confidence interval (CI): 101-180)) than CoNS (mean 42 (CI: 31-53)). S. aureus also correlated with a higher erythrocyte sedimentation rate value (ESR) (mean 67 (CI: 55-79)) than CoNS (mean 47 (CI: 39-54)).
机译:我们的目的是评估挪威感染的全髋关节置换术(THA)中的细菌发现。我们还想调查因果细菌与血液学发现之间的关系。确定了在1993年至2007年9月期间因全髋关节置换术后感染而向挪威置换术注册中心(NAR)报告的修订。一名观察员访问了十家代表性医院,这些医院收集了临床病史,术前血液样本和术中样本的细菌发现。在278个修订版中发现了两个或多个样本中的细菌生长,因此将其包括在内。鉴定出以下细菌:凝固酶阴性葡萄球菌(CoNS)(41%),金黄色葡萄球菌(S. aureus)(19%),链球菌(11%),多微生物感染(10%),肠球菌(9%),革兰氏-阴性细菌(6%)和其他细菌(4%)。 CoNS是整个时期最常见的细菌,但在急性术后感染(<3周)中,金黄色葡萄球菌是最常见的细菌。我们发现细菌组的分布没有随时间变化。金黄色葡萄球菌似乎与CoNS的C反应蛋白值(CRP)(平均值140(95%置信区间(CI):101-180))较高(平均值42(CI:31-53))相关。金黄色葡萄球菌还与比CoNS(平均值47(CI:39-54))更高的红细胞沉降率值(ESR)(平均值67(CI:55-79))相关。

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