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首页> 外文期刊>The Open Pediatric Medicine Journal >The Relationship Between Body Weight and Objective Measures of AirwayObstruction in Children
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The Relationship Between Body Weight and Objective Measures of AirwayObstruction in Children

机译：体重与儿童气道阻塞客观指标的关系

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Objective: The purpose of this study was to describe the effects of obesity (body mass index ≥ 95th percentile) on objective measures of airway obstruction as determined by spirometry. Design: Prospective cross-sectional study.Methods: Two hundred ninty six (Age: 13.6 ± 1.5 Years) children from two middle schools were enrolled. The standing heights and weights in bear-feet were measured, and body mass index (BMI) was calculated. Spirometry was performed according to the American Thoracic Society guidelines. The definition of reversible airway obstruction was based on the following criteria: forced expiratory volume in one second (FEV1) < 80% predicted, and FEV1/forced vital capacity (FVC) > 5% lower than predicted for age and sex. Results: Two-hundred-twenty-six children (76%) were African-American and 71 children (24%) were white. 138 (46%) children were obese. 36/296 (12%) children met the criteria for reversible airway obstruction, of which 29/296 (9.7%) were obese. Baseline FEV1 percent predicted (88 ± 6 vs 84 ± 7 %, p = 0.03), FEV1 /FVC(94 ± 6 vs 86 ± 8, p < 0.001), and FEV1 percent predicted following albuterol administration (95 ± 7 vs 88 ± 7 %, p = 0.03) were all lower in children who were obese.Conclusions: There is an association between obesity and reversible airway obstruction as demonstrated by spirometry in children.
机译：目的：本研究旨在描述肥胖（体重指数≥95％）对通过肺活量测定法确定的气道阻塞客观指标的影响。设计：前瞻性横断面研究。方法：招收来自两所中学的696名儿童（年龄：13.6±1.5岁）。测量熊脚的身高和体重，并计算体重指数（BMI）。肺活量测定是根据美国胸科学会的指南进行的。可逆性气道阻塞的定义基于以下标准：一秒钟的强制呼气量（FEV1）<预测值的80％，FEV1 /强制肺活量（FVC）低于年龄和性别预测值的5％。结果：262名儿童（76％）为非裔美国人，71名儿童（24％）为白人。 138名（46％）儿童肥胖。 36/296（12％）的儿童符合可逆性气道阻塞的标准，其中29/296（9.7％）肥胖。预测的基线FEV1％（88±6 vs 84±7％，p = 0.03），FEV1 / FVC（94±6 vs 86±8，p <0.001）和沙丁胺醇给药后预测的FEV1％（95±7 vs 88± 7％（p = 0.03）在肥胖儿童中均较低。结论：肺活量测定表明，肥胖与可逆性气道阻塞之间存在关联。

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