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首页> 外文期刊>The Turkish journal of pediatrics. >Comparison of endotracheal aspirate and non-bronchoscopic bronchoalveolar lavage in the diagnosis of ventilator-associated pneumonia in a pediatric intensive care unit
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Comparison of endotracheal aspirate and non-bronchoscopic bronchoalveolar lavage in the diagnosis of ventilator-associated pneumonia in a pediatric intensive care unit

机译：儿科重症监护室气管内吸出物与非支气管镜支气管肺泡灌洗术对呼吸机相关性肺炎的诊断比较

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Ventilator-associated pneumonia (VAP) is defined as pneumonia occuring in any period of mechanical ventilation. There is no optimal diagnostic method in current use and in this study we aimed to compare two non-invasive diagnostic methods used in diagnosis of VAP in children. This prospective study was conducted in 8 bedded Pediatric Intensive Care Unit at Ege University Children′s Hospital. Endotracheal aspiration (ETA) and non-bronchoscopic bronchoalveolar lavage (BAL) were performed in case of developing VIP after 48 hours of ventilation. Quantitative cultures were examined in Ege University Department of Diagnostic Microbiology, Bacteriology Laboratory. Fourty-one patients were enrolled in the study. The mean age of study subjects was 47.2±53.6 months. A total of 28 in 82 specimens taken with both methods were negativeegative; 28 had positive result with ETA and a negative result with non-bronchoscopic BAL and both results were negative in 26 specimens. There were no patients whose respiratory specimen culture was negative with ETA and positive with non-bronchoscopic BAL. These results imply that there is a significant difference between two diagnostic methods (p0.001). Negative non-bronchoscopic BAL results are recognized as absence of VAP; therefore, ETA results were compared with this method. ETA’s sensitivity, specificity, negative and positive predictive values were 100%, 50%, 100% and 48% respectively. The study revealed the ease of usability and the sensitivity of non-bronchoscopic BAL, in comparison with ETA.
机译：呼吸机相关性肺炎（VAP）定义为在任何机械通气期间发生的肺炎。当前没有最佳的诊断方法，在这项研究中，我们旨在比较两种用于诊断儿童VAP的非侵入性诊断方法。这项前瞻性研究是在Ege大学儿童医院的8床小儿重症监护室进行的。通气48小时后出现VIP时，进行气管内抽吸（ETA）和非支气管镜支气管肺泡灌洗（BAL）。在Ege大学细菌学诊断微生物学系检查定量培养。这项研究招募了41位患者。研究对象的平均年龄为47.2±53.6个月。两种方法采集的82个样本中共有28个阴性/阴性。 28例ETA阳性，非支气管镜BAL阴性，26例标本均为阴性。没有患者的呼吸道标本培养对ETA阴性而对非支气管镜BAL阳性。这些结果表明，两种诊断方法之间存在显着差异（p <0.001）。非支气管镜BAL阴性结果被认为是VAP缺失;因此，将ETA结果与该方法进行了比较。 ETA的敏感性，特异性，阴性和阳性预测值分别为100％，50％，100％和48％。研究显示，与ETA相比，非支气管镜BAL的易用性和敏感性。

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