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首页> 外文期刊>Therapeutic advances in drug safety. >Educational intervention to improve the knowledge, attitude and practice of healthcare professionals regarding pharmacovigilance in South-South Nigeria
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Educational intervention to improve the knowledge, attitude and practice of healthcare professionals regarding pharmacovigilance in South-South Nigeria

机译：在尼日利亚南部和南部进行教育干预以提高医疗保健专业人员对药物警戒的知识，态度和实践

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Our aim in this study was to evaluate the effect of a combined educational intervention and year-long monthly text message reinforcements via the Short Messaging System (SMS) on the knowledge, attitude and practice (KAP) of healthcare professionals (HCPs) towards pharmacovigilance. Six randomly selected teaching hospitals in the South-South zone of Nigeria were randomized in 1:1 ratio into intervention and control groups. The educational intervention consisted of delivering a seminar followed by sending monthly texts message reinforcements via SMS over 12?months. Then a semi-structured questionnaire regarding the KAP of pharmacovigilance was completed by HCPs working in the hospitals after the intervention. Data was analysed descriptively and inferentially. A total of 931 HCPs participated in the post intervention study (596 in the intervention and 335 in the control). The M:F ratio was 1:1.5. According to the KAP questionnaire, a significant difference was observed between the intervention and control groups, regarding knowledge of the types of adverse drug reactions (ADRs). ADR resulting from pharmacological action of the drug (85.6% versus 77%, p = 0.001), the fact that ADRs can persist for a long time; (60.1% versus 53.4%, p = 0.024) and a higher awareness of the ADR reporting form (48.7% versus 18.8%, p 0.001). Most respondents in the intervention group (68.5% versus 60.6%, p = 0.001) believed they should report ADRs even if they were unsure an ADR has occurred, a greater proportion of HCPs from the intervention group had significantly observed an ADR (82% versus 73.4%, p = 0.001). Furthermore, of the 188 who had ever reported an ADR, 41% from the intervention group used the national ADR reporting form compared with 19.8% from the controls (p 0.001). This educational intervention and the use of SMS as a reinforcement tool appeared to have positively impacted on the knowledge and practice of pharmacovigilance in South-South Nigeria with a less-than-impressive change in attitude. Continuous medical education may be required to effect long-lasting changes.
机译：我们在这项研究中的目的是评估通过短信系统（SMS）进行的教育干预和为期一年的每月每月短信增强相结合对医疗专业人员（HCP）对药物警戒的知识，态度和实践（KAP）的影响。将尼日利亚南南地区的六家随机选择的教学医院按1：1比例随机分为干预组和对照组。教育干预包括举办研讨会，然后在12个月内通过SMS每月发送短信增强功能。然后，由干预后在医院工作的HCP完成关于药物警戒性KAP的半结构式问卷调查。对数据进行描述性和推断性分析。总共931名HCP参加了干预后研究（干预中596名，对照中335名）。 M：F比为1：1.5。根据KAP问卷，在药物不良反应（ADR）类型的知识方面，干预组和对照组之间存在显着差异。 ADR是由药物的药理作用引起的（85.6％对77％，p = 0.001），这一事实表明ADR可以长期持续存在; （分别为60.1％和53.4％，p = 0.024）和对ADR报告形式的较高意识（48.7％和18.8％，p <0.001）。干预组中的大多数受访者（68.5％对60.6％，p = 0.001）认为，即使他们不确定发生了ADR，他们也应报告ADR，干预组中更大比例的HCP明显观察到了ADR（82％对73.4％，p = 0.001）。此外，在曾经报告过ADR的188名患者中，干预组中有41％使用了国家ADR报告表，而对照组中只有19.8％（p <0.001）。这种教育干预以及将SMS用作强化工具似乎对尼日利亚南部和南部地区药物警戒的知识和实践产生了积极的影响，其态度的变化并不令人印象深刻。可能需要进行持续医学教育以实现长期的变化。

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