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首页> 外文期刊>Translational Research in Oral Oncology >The impact of comorbidities on the management and prognosis of oropharyngeal and hypopharyngeal cancer patients in Taiwan:
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The impact of comorbidities on the management and prognosis of oropharyngeal and hypopharyngeal cancer patients in Taiwan:

机译：合并症对台湾口咽和下咽癌患者管理和预后的影响：

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Background:Comorbidity is often associated with negative outcome of prognosis. The aim of this study was to investigate the prevalence and impact of comorbidities in a retrospective nationwide population-based study of patients with oropharyngeal and hypopharyngeal cancers in Taiwan.Materials and Methods:A total of 4733 oropharyngeal and hypopharyngeal cancer patients diagnosed in the period 2007–2010 were identified through the Taiwan Cancer Registry (TCR) database. By linking this data set to the National Health Insurance Research Database (NHIRD) and the Death Registry (DR), information on comorbidity and cause of death was obtained and adapted to the Charlson’s comorbidity index (CCI). The influence of comorbidity on overall survival and cancer-related death was evaluated by Kaplan–Meier estimates and Cox regressions.Results:There were 23.5% of patients with comorbidities during the year before cancer diagnosis. Patients with comorbidities are associated with lower survival rates for stage 3 and for o...
机译：背景：合并症通常与预后不良有关。这项研究的目的是在一项针对台湾口咽癌和咽喉癌患者的全国性回顾性研究中调查合并症的患病率和影响。材料与方法：2007年期间确诊的4733例咽喉癌和咽喉癌患者通过台湾癌症登记处（TCR）数据库确定了–2010年。通过将此数据集与国家健康保险研究数据库（NHIRD）和死亡登记处（DR）链接，可以获得有关合并症和死亡原因的信息，并使其适应于查尔森合并症指数（CCI）。通过Kaplan–Meier估计和Cox回归评估合并症对整体生存和与癌症相关的死亡的影响。结果：在癌症诊断前一年中，合并症患者占23.5％。合并症患者的3期和0期生存率较低。

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