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首页> 外文期刊>Turkish Journal of Veterinary and Animal Sciences >Potential future applications of spermatheca extract from the marine snail Telescopium telescopium
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Potential future applications of spermatheca extract from the marine snail Telescopium telescopium

机译：海洋蜗牛Telescopium telescopium中的精囊提取物的潜在未来应用

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摘要

Cytosol fraction of spermatheca and/or the ovotestis gland from the marine snail Telescopium telescopium was found to have antimicrobial, antiprotozoal, antifertility, and immunomodulation properties. The present experiment was conducted to explore the biochemical nature, composition, and pharmacological properties of the cytosol fraction along with its toxicity on the hematopoietic system in vivo. This glandular extract was analyzed and found to contain enzymes, hormones, minerals, vitamins, and other biologically active components like higher vertebrates. The present study showed that the extract was able to restrict the induced tumor (sarcoma-180) growth in mice concomitantly with an increased life span of the tumor bearing mice, but without any hematopoietic toxicity. This antitumor property was thought to be mediated immunologically as also found in other aspects of pharmacological actions of this extract; hence, it could be developed as a potent immunomodulator to be used for various pathological conditions in general, but in cancer in particular.
机译：发现来自海洋蜗牛Telescopium telescopium的精囊和/或卵形睾丸的细胞溶胶部分具有抗微生物，抗原生动物，抗生育和免疫调节特性。进行本实验以探索细胞溶质级分的生化性质，组成和药理特性，以及其对体内造血系统的毒性。经分析，该腺提取物含有酶，激素，矿物质，维生素和其他生物活性成分，例如高等脊椎动物。本研究表明，提取物能够限制小鼠中诱导的肿瘤（肉瘤180）的生长，同时增加了荷瘤小鼠的寿命，但没有任何造血毒性。这种抗肿瘤特性被认为是通过免疫学介导的，在这种提取物的药理作用的其他方面也发现了这种特性。因此，它可以发展成为一种强效的免疫调节剂，通常用于各种病理状况，尤其是在癌症中。

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