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Large hibernoma of the neck: A case report

机译:颈部大型子宫瘤:一例报告

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Introduction. A hibernoma is a rare benign tumor derived from vestigial remnants of brown adipose tissue. In neonates this tissue makes up about 5% of the body mass and its amount greatly decreases after birth, persisting only in scattered subcutaneous areas. In rare cases, brown fat continues to grow leading to a hibernoma that may be located in the head and neck. We present an illustrative case of a large hibernoma of the neck with infraclavicular extension and discuss about diagnostic and treatment difficulties. Case report. A 29-year-old male presented with large, slowly progressive, painless neck mass that was noticed 6 months earlier. Computed tomography (CT) and magnetic resonance (MR) showed a well-vascularized, soft tissue tumor of the lateral region of the neck and supraclavicular fossa with extension below clavicle. Treatment included arterial embolization followed by challenging surgical removal of the tumor. Dissection was performed at III, IV and V levels of the neck, making complete resection possible without the tumor fragmentation or major blood vessels and cranial nerves injuries. The final diagnosis of the hibernoma was made by histopathological analysis. The patient had no signs of recurrence during three-year follow-up. Conclusion. Although the CT scan and MR may raise the suspicion, hibernoma is definitely diagnosed by a pathologist. It is very important to exclude the malignant processes, foremost liposarcoma. The tumor fragmentation during surgery should be avoided because the high vascularity of the tumor tissue carries a substantial risk for hemorrhage. Our experience with preoperative embolization and complete tumor resection in this case showed positive impact on the final outcome.
机译:介绍。纤维瘤是一种罕见的良性肿瘤,其源于棕色脂肪组织的残留物。在新生儿中,该组织约占体重的5%,出生后其数量会大大减少,仅在分散的皮下区域存在。在极少数情况下,棕色脂肪会继续增长,导致可能位于头部和颈部的冬眠瘤。我们提出了一个具有锁骨下延伸的颈部大型子宫瘤的病例,并讨论了诊断和治疗的困难。案例报告。一位29岁的男性表现出较大,缓慢进行性,无痛的颈部肿块,六个月前就被发现。计算机断层扫描(CT)和磁共振(MR)显示颈部和锁骨上窝外侧区域的血管良好,软组织肿瘤,并在锁骨下方延伸。治疗包括动脉栓塞,然后挑战性手术切除肿瘤。在颈部的III,IV和V水平进行了解剖,使得完全切除成为可能,而没有肿瘤碎片或主要血管和颅神经受伤。通过组织病理学分析来最终诊断为冬眠瘤。该患者在三年的随访中没有复发的迹象。结论。尽管CT扫描和MR可能引起怀疑,但病理学家肯定诊断出了冬眠瘤。排除恶性过程,最重要的是脂肪肉瘤。应避免手术过程中的肿瘤碎裂,因为肿瘤组织的高血管具有大量出血的风险。我们在这种情况下的术前栓塞和完整肿瘤切除的经验显示出对最终结果的积极影响。

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