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首页> 外文期刊>World Journal of Vaccines >Porcine Circovirus 2: Immunopathogenesis and Recent Developments in Vaccines
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Porcine Circovirus 2: Immunopathogenesis and Recent Developments in Vaccines

机译：猪圆环病毒2：疫苗的免疫发病机制和最新进展

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Porcine circovirus 2 (PCV2) is currently considered an important etiologic agent of swine and its infection has potentially serious economic impact on the swine industry worldwide. This virus is frequently associated with postweaning multisystemic wasting syndrome (PMWS), and also with other clinical conditions such as porcine dermatitis and nephropathy syndrome (PDNS), late-term abortions, reproductive failure in sows, proliferative and necrotizing pneumonia and congenital tremors. The term porcine circovirus-associated disease (PCVAD) is currently used to refer to any of these diseases when they are associated with PCV2 infection. The PCV2 was recognized as a pathogen in 1997, and many questions regarding its biology and pathogenesis remain unanswered. Currently, some studies have shown the production of new vaccine candidates and field efficacy testing of commercial vaccines. This review discusses some major points concerned with immunopathogenesis and vaccines for PCV2 infection.
机译：猪圆环病毒2（PCV2）当前被认为是猪的重要病原体，其感染可能对全世界的猪业产生严重的经济影响。该病毒通常与断奶后多系统消耗综合症（PMWS）以及其他临床疾病有关，例如猪皮炎和肾病综合症（PDNS），后期流产，母猪生殖衰竭，增生性坏死性肺炎和先天性震颤。目前，术语猪圆环病毒相关疾病（PCVAD）是指与PCV2感染相关的任何这些疾病。 PCV2在1997年被确认为病原体，有关其生物学和发病机理的许多问题仍未得到解答。当前，一些研究已经显示出新疫苗候选物的生产和商业疫苗的现场功效测试。这篇评论讨论了有关PCV2感染的免疫发病机制和疫苗的一些要点。

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