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Research fatigue among injecting drug users in Karachi, Pakistan

机译:巴基斯坦卡拉奇的注射吸毒者中的疲劳研究

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Background Karachi is the largest metropolis of Pakistan and its economic hub attracting domestic migrants for economic opportunities. It is also the epicenter of HIV epidemic in the country. Since 2004, one pilot study and four behavioral and biological surveillance rounds have been conducted in Karachi. In addition many student research projects have also focused on key risk groups including injection drug users (IDUs). As a result of this extra ordinary exposure of same kind of questions, IDUs know how to respond to high value questions related to sharing of needles or unsafe sexual practices. The purpose of the study was to explore the element of research fatigue among IDUs in Karachi, Pakistan. Methods The study was conducted on 32 spots in Karachi, selected on the basis of estimate of IDUs at each spot. A trained field worker (recovered IDU) visited each spot; observed sharing behavior of IDUs and asked questions related to practices in January 2009. Verbal consent was obtained from each respondent before asking questions. Results On average 14 IDUs were present at each spot and out of 32 selected spots, 81% were active while more than two groups were present at 69% spots. In each group three to four IDUs were present and everyone in the group was sharing. One dose of injecting narcotics was observed. Sharing of syringes, needles and distilled water was observed at 63% spots while professional injector/street doctor was present at 60% spots. Conclusion There is a need to check internal consistency in surveillance research. It is highly likely that IDUs and other risk groups know how to respond to key questions but their responses do not match with the practices.
机译:背景卡拉奇是巴基斯坦最大的大都市,其经济中心吸引着国内移民寻求经济机会。它也是该国艾滋病毒流行的中心。自2004年以来,在卡拉奇进行了一项试点研究以及四轮行为和生物监视。此外,许多学生研究项目也将重点放在包括注射毒品使用者(IDU)在内的主要风险人群上。由于这种常见问题的普遍暴露,注射毒品使用者知道如何回答与共用针头或不安全的性行为有关的高价值问题。这项研究的目的是探讨巴基斯坦卡拉奇的注射毒品使用者中研究疲劳的因素。方法本研究在卡拉奇的32个地点进行,根据每个地点的吸毒者估计数进行选择。训练有素的现场工作人员(回收的IDU)参观了每个地点。在2009年1月观察到IDU的共享行为并询问了与行为有关的问题。在询问问题之前,已从每个受访者获得口头同意。结果每个斑点平均存在14个IDU,在选定的32个斑点中,有81%处于活动状态,而两组中有69%的斑点活跃。在每个小组中,有三到四个IDU,小组中的每个人都在共享。观察到一剂注射麻醉剂。观察到有63%的斑点共用注射器,针头和蒸馏水,而有60%的斑点是专业的注射器/街头医生。结论在监视研究中需要检查内部一致性。注射毒品使用者和其他风险群体很可能知道如何回答关键问题,但他们的回答与做法不符。

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