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首页> 外文期刊>Hong Kong Journal of Paediatrics >Endoscopic Treatment of Gastroesophageal Varices: Efficacy and Safety in Children
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Endoscopic Treatment of Gastroesophageal Varices: Efficacy and Safety in Children

机译：内镜治疗胃食管静脉曲张：儿童的疗效和安全性

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Purpose: Our purpose was to evaluate the efficacy and safety of endoscopic variceal band ligation (EVL) and Histoacryl injection for the treatment of gastroesophageal varices in children. Risk factors of rebleeding were analysed preliminarily. Methods: 15 children with esophageal varices and/or gastric varices who received EVL and/or Histoacryl injection were enrolled at our endoscopy center between October 2009 and March 2012. Demographic data, clinical characteristics and endoscopic data were registered and analysed as a Single-center prospective study. Results: The mean age was 9.5±3.3 years (2.5-14.3 years). The mean of clinical follow-up was 13.0±10.8 months (range 1-30 months). EVL and/or Histoacryl injection was successfully performed in all children. Immediate control of bleeding was achieved in all cases. The number of rubber bands placed in all patients ranged from 2 to 6. Early slippage of the rubber bands were not been found in the post-EVL rebleeding. Varices relapse with rebleeding was observed in 4 of 15 (26.7%) patients after a mean time of 14.8±6.5 weeks (5-24 weeks) follow-up. Patients with variceal rebleeding were retreated. Aggravated coagulation state, decreased platelets and ascites may be meaningful in predicting rebleeding. During follow-up, no fatal complication was observed in the patients. Conclusion: In children, the use of EVL and Histoacryl injection is safe and effective for the treatment of gastroesophageal varices. Effective measures for prevention and treatment of rebleeding should be adopted before and after operation.
机译：目的：我们的目的是评估内镜下静脉曲张带结扎术（EVL）和组织丙烯酸注射液治疗儿童胃食管静脉曲张的疗效和安全性。初步分析了再出血的危险因素。方法：从2009年10月至2012年3月，在我们的内窥镜中心招募15例接受EVL和/或组织丙烯酸注射的食管静脉曲张和/或胃静脉曲张患儿。将人口统计学资料，临床特征和内窥镜检查数据作为单中心进行分析。前瞻性研究。结果：平均年龄为9.5±3.3岁（2.5-14.3岁）。临床随访的平均时间为13.0±10.8个月（范围1-30个月）。所有儿童均成功进行了EVL和/或Histoacryl注射。在所有情况下都可以立即控制出血。在所有患者中放置的橡皮筋的数量为2至6。在EVL后再出血中未发现橡皮筋的早期滑动。平均随访14.8±6.5周（5-24周）后，在15例患者中有4例（26.7％）观察到静脉曲张复发。患有静脉曲张再出血的患者均接受治疗。凝血状态加重，血小板和腹水减少对预测再出血可能有意义。在随访过程中，未观察到致命并发症。结论：在儿童中，EVL和组织丙烯酸注射液治疗胃食管静脉曲张是安全有效的。手术前后应采取有效的预防和治疗再出血的措施。

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