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首页> 外文期刊>Hong Kong Journal of Paediatrics >Serum Vitamin B12 Status in Children with Familial Mediterranean Fever Receiving Colchicine Treatment
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Serum Vitamin B12 Status in Children with Familial Mediterranean Fever Receiving Colchicine Treatment

机译：接受秋水仙碱治疗的家族性地中海热患儿的血清维生素B12状况

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Aims: The aim of this study was to determine the effect of colchicine on serum vitamin B12 status in children with Familial Mediterranean Fever (FMF). Settings and Design: The Tel Hashomer criteria had been used to establish the diagnosis of FMF. Colchicine treatment was initiated by age based dosage schedule to each patient. Methods and Material: This study was cross sectional. Serum vitamin B12 levels were measured before and during colchicine treatment in 42 children with FMF. Results: Twenty- two girls and 20 boys, with a mean age of 11.7±0.5 years, were included in the study. The mean duration of colchicine treatment was 2.5±2.6 years. The daily colchicine doses ranged between 0.0077 to 0.0741 mg/kg. There was a significant difference between first and control visit mean serum vitamin B12 levels, 418 pg/ml and 240 pg/ml respectively (p
机译：目的：本研究的目的是确定秋水仙碱对家族性地中海热（FMF）患儿血清维生素B12状态的影响。设置和设计：Tel Hashomer标准已用于建立FMF的诊断。秋水仙碱的治疗是通过针对每个患者的基于年龄的给药方案开始的。方法和材料：本研究为横断面。在秋水仙碱治疗之前和期间，对42名FMF患儿的血清维生素B12水平进行了测定。结果：该研究包括22名女孩和20名男孩，平均年龄为11.7±0.5岁。秋水仙碱的平均治疗时间为2.5±2.6年。秋水仙碱的每日剂量在0.0077至0.0741 mg / kg之间。首次访视和对照访视的平均血清维生素B12水平分别为418 pg / ml和240 pg / ml之间存在显着差异（p

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