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首页> 外文期刊>Hong Kong Journal of Paediatrics >Application of Flexible Bronchoscopy in the Aetiological Diagnosis of Childhood Refractory Wheezing
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Application of Flexible Bronchoscopy in the Aetiological Diagnosis of Childhood Refractory Wheezing

机译：柔性支气管镜在儿童难治性喘息的病因诊断中的应用

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Objective: To explore the value of flexible bronchoscopy in aetiological diagnosis of paediatric refractory wheezing. Methods: A total of 246 patients with refractory wheezing performed flexible bronchoscopy were analysed. They were 146 males and 100 females with a ratio of male to female 1.5:1. Their age ranged from 1 month to 9 years with a median age of 17 months. Results: Flexible bronchoscopy was performed 269 times. By bronchoscopy, mucus plug was found in 52 patients (21.1%), airway malacia in 76 (30.9%), structural deformity in 32 (13.0%), foreign bodies in 22 (8.9%), tuberculosis in 3 and tumor in one. The aetiology of refractory wheezing varied with different ages. Airway malacia (61.2%) was the main reason in infants, then mucus plug (15.3%). Among toddlers, the most common reason was mucus plug (24.5%), followed by airway malacia (15.1%) and foreign body (14.2%). Bronchoalveolar lavage demonstrated pathogens in 17 (17.3%) of 98 samples. The most common complication was hypoxia during the procedures. They all were transient and alleviated by oxygen supplement or temporary cessation of the procedure. Conclusion: Flexible bronchoscopy is effective in the aetiological diagnosis of childhood refractory wheezing. Mucus plug, airway malacia, structural deformities and foreign body are the main reasons for childhood refractory wheezing.
机译：目的：探讨柔性支气管镜检查在小儿难治性喘息病因诊断中的价值。方法：对246例行软支气管镜检查的难治性喘息患者进行分析。他们是146名男性和100名女性，男女比例为1.5：1。他们的年龄从1个月到9岁不等，平均年龄为17个月。结果：柔性支气管镜检查进行了269次。支气管镜检查发现粘液堵塞52例（21.1％），气道软化症76例（30.9％），结构畸形32例（13.0％），异物22例（8.9％），结核3例，肿瘤1例。难治性喘息的病因因年龄而异。气道软化症（61.2％）是婴儿的主要原因，其次是粘液堵塞（15.3％）。在幼儿中，最常见的原因是粘液堵塞（24.5％），其次是气道软化症（15.1％）和异物（14.2％）。支气管肺泡灌洗显示98个样品中的17个（17.3％）病原体。手术中最常见的并发症是缺氧。他们都是短暂的，可以通过补充氧气或暂时停止手术来缓解。结论：柔性支气管镜检查对儿童难治性喘息的病因诊断有效。粘液堵塞，气道软化症，结构畸形和异物是儿童难治性喘息的主要原因。

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