• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Database >iPathCons and iPathDB: an improved insect pathway construction tool and the database
【24h】

iPathCons and iPathDB: an improved insect pathway construction tool and the database

机译：iPathCons和iPathDB：改进的昆虫通道构建工具和数据库

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Insects are one of the most successful animal groups on earth. Some insects, such as the silkworm and honeybee, are beneficial to humans, whereas others are notorious pests of crops. At present, the genomes of 38 insects have been sequenced and made publically available. In addition, the transcriptomes of dozens of insects have been sequenced. As gene data rapidly accumulate, constructing the pathway of molecular interactions becomes increasingly important for entomological research. Here, we developed an improved tool, iPathCons, for knowledge-based construction of pathways from the transcriptomes or the official gene sets of genomes. Considering the high evolution diversity in insects, iPathCons uses a voting system for Kyoto Encyclopedia of Genes and Genomes Orthology assignment. Both stand-alone software and a web server of iPathCons are provided. Using iPathCons, we constructed the pathways of molecular interactions of 52 insects, including 37 genome-sequenced and 15 transcriptome-sequenced ones. These pathways are available in the iPathDB, which provides searches, web server, data downloads, etc. This database will be highly useful for the insect research community. Database URL: http://ento.njau.edu.cn/ipath/
机译：昆虫是地球上最成功的动物之一。一些昆虫，例如蚕和蜜蜂，对人类有益，而另一些则是农作物的臭虫。目前，已经对38种昆虫的基因组进行了测序并公开提供。另外，已经对数十种昆虫的转录组进行了测序。随着基因数据的迅速积累，构建分子相互作用的途径对于昆虫学研究变得越来越重要。在这里，我们开发了一种改进的工具iPathCons，用于从转录组或基因组的官方基因组进行基于知识的途径构建。考虑到昆虫的高度进化多样性，iPathCons使用投票系统对《京都议定书》进行基因和基因组拼写检查。提供了独立软件和iPathCons的Web服务器。使用iPathCons，我们构建了52种昆虫的分子相互作用的途径，其中包括37个基因组测序的昆虫和15个转录组测序的昆虫。这些路径在iPathDB中可用，该路径提供搜索，Web服务器，数据下载等。此数据库对昆虫研究界非常有用。数据库网址：http://ento.njau.edu.cn/ipath/

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号