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Recurrent Aphthous Stomatitis – a Reflection of Gastrointestinal Diseases?

机译：复发性口疮性口炎-胃肠道疾病的反映？

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Abstract Recurrent oral ulceration is a common condition accompanied by pain which often interferes with food intake and speaking. A variety of etiological factors can contribute to oral ulceration, e.g. local factors, such as trauma or viral infection, or systemic diseases that manifest in the oral cavity. Recurrent aphthous stomatitis (RAS) is one of the most frequently diagnosed condition characterized by repeated appearance of oral ulcers. Clinical features of RAS are not homogenous (different ulcer types, different severity of the disease), and the etiology is unclear. No objective criteria are known for definitive RAS diagnosis, and descriptive criteria are not well-defined. The majority of RAS cases are believed to be idiopathic, but some can be associated with an underlying systemic diseases, including nutritional deficiencies and inflammatory conditions. RAS is relatively often described to be associated with inflammatory diseases of gastrointestinal tract, and sometimes oral manifestation precedes gastrointestinal symptoms.Therefore, dentists might help to diagnose a range of systemic diseases. In the present review, the literature on most commonly RAS-associated conditions, inflammatory diseases associated with gastrointestinal tract, has been analyzed, providing practical tips helping to differentiate between idiopathic RAS and RAS accompanying systemic disease, and to facilitate adequate ulcer management.
机译：摘要复发性口腔溃疡是常见的伴有疼痛的症状，经常会影响食物的摄取和说话。多种病因可导致口腔溃疡，例如口腔溃疡。局部因素，例如创伤或病毒感染，或口腔中出现的全身性疾病。复发性口疮性口炎（RAS）是最常见的一种疾病，其特征是反复出现口腔溃疡。 RAS的临床特征不均一（溃疡类型不同，疾病严重程度不同），病因尚不清楚。对于确定的RAS诊断，尚无客观标准，描述性标准也不明确。据信大多数RAS病例是特发性的，但有些可能与潜在的系统性疾病有关，包括营养缺乏和炎症。 RAS通常被认为与胃肠道炎症有关，有时口腔表现先于胃肠道症状，因此，牙医可能有助于诊断多种系统性疾病。在本综述中，已对有关最常见的RAS相关疾病（与胃肠道相关的炎性疾病）的文献进行了分析，提供了实用的技巧，有助于区分特发性RAS和伴随全身性疾病的RAS，并有助于适当的溃疡管理。

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