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首页> 外文期刊>Dermatology Research and Practice >The Effect of Q-Switched Nd:YAG 1064 nm/532 nm Laser in the Treatment of Onychomycosis In Vivo
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The Effect of Q-Switched Nd:YAG 1064 nm/532 nm Laser in the Treatment of Onychomycosis In Vivo

机译：调Q Nd：YAG 1064 nm / 532 nm激光对体内甲癣的治疗作用

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In this prospective clinical study, the Q-Switched Nd:YAG 1064 nm/532 nm laser (Light Age, Inc., Somerset, NJ, USA) was used on 131 onychomycosis subjects (94 females, 37 males; ages 18 to 68 years). Mycotic cultures were taken and fungus types were detected. The laser protocol included two sessions with a one-month interval. Treatment duration was approximately 15 minutes per session and patients were observed over a 3-month time period. Laser fluencies of 14 J/cm2were applied at 9 billionths of a second pulse duration and at 5 Hz frequency. Follow-up was performed at 3 months with mycological cultures. Before and after digital photographs were taken. Adverse effects were recorded and all participants completed “self-evaluation questionnaires” rating their level of satisfaction. All subjects were well satisfied with the treatments, there were no noticeable side effects, and no significant differences were found treating men versus women. At the 3-month follow-up 95.42% of the patients were laboratory mycologically cured of fungal infection. This clinical study demonstrates that fungal nail infections can be effectively and safely treated with Q-Switched Nd:YAG 1064 nm/532 nm laser. It can also be combined with systemic oral antifungals providing more limited treatment time.
机译：在这项前瞻性临床研究中，将Q开关Nd：YAG 1064 nm / 532 nm激光（Light Age，Inc.，萨默塞特，新泽西州，美国）用于131例灰指甲病患者（94名女性，37名男性;年龄在18至68岁之间） ）。进行真菌培养并检测真菌类型。激光治疗方案包括两个疗程，间隔为一个月。治疗持续时间约为每个疗程15分钟，并在3个月的时间内观察到患者。在9十分之一秒的脉冲持续时间和5 atHz的频率下施加了14 J / cm2的激光通量。在3个月时进行了真菌培养的随访。数码照片拍摄前后。记录不良反应，所有参与者填写“自我评估问卷”，对他们的满意度进行评分。所有受试者对治疗都非常满意，没有明显的副作用，并且在治疗男女之间没有发现显着差异。在3个月的随访中，有95.42％的患者在实验室通过真菌学方法治愈了真菌感染。这项临床研究表明，使用Q开关Nd：YAG 1064 nm / 532 nm激光可以有效，安全地治疗真菌性指甲感染。它也可以与全身性口服抗真菌药联合使用，从而缩短治疗时间。

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