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首页> 外文期刊>Dental Press Journal of Orthodontics >Macroscopic and microscopic evaluation of flapless alveolar perforations on experimental tooth movement
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Macroscopic and microscopic evaluation of flapless alveolar perforations on experimental tooth movement

机译：无瓣肺泡穿孔对实验牙齿运动的宏观和微观评估

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Objective: The aim of this study was to evaluate a flapless surgical technique as an alternative to traditional alveolar corticotomy used to accelerate orthodontic tooth movement (OTM). Methods: To induce OTM in Wistar rats, 40 cN of orthodontic force were applied to the maxillary left first molars. Forty rats were distributed into control groups (CG1, CG3, CG7 and CG14) and experimental groups ( n = 5), in which alveolar perforations were made using a spear-shaped guide bur (EG1, EG3, EG7, EG14). Euthanasia dates were set at 1, 3, 7 and 14 days, respectively, after tooth movement began. The amount of OTM was measured with a caliper, and osteoclasts present in the periodontal ligament of the mesial root of the moved tooth were counted by means of histological evaluation (tartrate-resistant acid phosphatase staining, TRAP). Results: Although there was no difference in the amount of OTM within subgroups of corresponding experimental periods ( p 0.05), when EG14 and CG14 were compared, a larger number of osteoclasts was counted in the experimental group ( p 0.00). Conclusion: The authors concluded that flapless cortical alveolar perforations led to more intense osteoclastic activity on the fourteenth day; nevertheless, no evidence of accelerated OTM could be noted.
机译：目的：本研究的目的是评估一种无瓣外科手术技术，以替代传统的用于加速正畸牙齿运动（OTM）的肺泡皮质切开术。方法：为了在Wistar大鼠中诱导OTM，对上颌左第一磨牙施加40 cN正畸力。将40只大鼠分为对照组（CG1，CG3，CG7和CG14）和实验组（n = 5），其中使用矛状导向针（EG1，EG3，EG7，EG14）制作肺泡穿孔。牙齿运动开始后，安乐死的日期分别定为1、3、7和14天。用卡尺测量OTM的量，并通过组织学评估（抗酒石酸酸性磷酸酶染色，TRAP）计数存在于运动的牙齿的牙根根的牙周膜中的破骨细胞。结果：尽管在相应实验期间的亚组中OTM的量没有差异（p> 0.05），但是当比较EG14和CG14时，实验组中破骨细胞的数量更多（p <0.00）。结论：作者得出结论，在第14天，无瓣皮层肺泡穿孔导致更强烈的破骨细胞活性。但是，没有发现加速OTM的迹象。

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