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Transformation of a glandular odontogenic cyst into mucoepidermoid carcinoma of the mandible: A case report

机译:腺牙源性囊肿转化为下颌粘液表皮样癌:一例报告

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The glandular odontogenic cyst (GOC) is a rare pathology of odontogenic origin, which can behave unpredictably. It is problematic in clinical, radiographic and histological diagnostics. Intraosseous mucoepidermoid carcinoma (MEC) is a rare tumor which affects the jaws, typically found in the mandible. This malignancy, which usually originates from the salivary glands, can also be caused by a transformation of the mucous cells found in odontogenic cysts. This article presents a rare case of GOC transforming into MEC of the mandible, which was reported during the treatment of a 52-year-old male patient. The aim of this work was to present some of the therapeutic and clinical difficulties encountered when GOC transforms into mucoepidermoid cancer in the mandible, considering the pathomorphological and histological differentiations. The differentiation between MEC and GOC might be difficult through microscopic examination and requires the cooperation of a clinician – a maxillofacial surgeon – and a histopathologist.
机译:腺牙源性囊肿(GOC)是牙源性起源的一种罕见病理,其行为可能无法预测。在临床,影像学和组织学诊断中存在问题。骨内粘液表皮样癌(MEC)是一种罕见的会影响颌骨的肿瘤,通常存在于下颌骨中。这种恶性肿瘤通常起源于唾液腺,也可能是由牙源性囊肿中粘液细胞的转化引起的。本文介绍了罕见病例,GOC转化为下颌骨MEC,在治疗一名52岁男性患者的过程中据报道。这项工作的目的是介绍考虑到病理形态学和组织学差异的GOC转变为下颌骨粘液表皮样癌时遇到的一些治疗和临床困难。通过显微镜检查可能难以区分MEC和GOC,并且需要临床医生(颌面外科医生)和组织病理学家的配合。

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