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首页> 外文期刊>Dental and Medical Problems >Serum Concentration of C-Reactive Protein in Patients Treated for Acute and Chronic Odontogenic Infections
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Serum Concentration of C-Reactive Protein in Patients Treated for Acute and Chronic Odontogenic Infections

机译：急性和慢性牙源性感染治疗的患者血清C反应蛋白的浓度

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Abstract Background . C-reactive protein (CRP) performs many important functions in the body, among which the binding, detoxification and elimination of tissue breakdown products seem to be the most important ones. CRP measurement is a fast and simple method for detecting inflammatory processes. Objectives . The aim of the study was to determine the serum CRP level in peripheral blood during acute and chronic odontogenic infections before and after surgical treatment. Material and Methods . Serum CRP levels were determined by immunochromatography. Blood samples were collected from the fingertip of study participants, and Actim CRP dipstick tests were performed prior to, 24 hours after and 7 days after surgical treatment. Results . There were no significant differences (p = 0.132) between the baseline CRP level and after 24 hours in the entire group with chronic infections. In patients with non-elevated baseline CRP, surgical intervention caused a CRP increase after 24 hours in 8 out of 11 of the subjects. In chronic periapical periodontitis, CRP was significantly lower after 7 days in 19 out of 20 subjects (p = 0.005). In acute infections, CRP was markedly elevated. After 7 days of therapy, a statistically significant (p = 0.0002) reduction of CRP by 40 mg/L was recorded in 16 subjects, however, CRP remained elevated compared to the normal range in 13 cases. Conclusion . Our study revealed significant CRP level variations depending on the type of odontogenic infection, treatment time and treatment itself. Although acute inflammation induced higher CRP values, chronic inflammation was still noticeable in the collected data.
机译：抽象背景。 C反应蛋白（CRP）在体内执行许多重要功能，其中结合，解毒和消除组织分解产物似乎是最重要的功能。 CRP测量是检测炎症过程的快速简便的方法。目标。该研究的目的是确定手术治疗前后急性和慢性牙源性感染期间外周血的血清CRP水平。材料与方法 。通过免疫色谱法测定血清CRP水平。从研究参与者的指尖采集血样，并在手术治疗之前，之后24小时和之后7天进行Actim CRP量油尺测试。结果。在整个慢性感染组中，基线CRP水平与24小时后无显着差异（p = 0.132）。在基线CRP不升高的患者中，手术干预导致11名受试者中的8名24小时后CRP升高。在慢性根尖周炎中，20名受试者中有19名受试者在7天后CRP显着降低（p = 0.005）。在急性感染中，CRP明显升高。治疗7天后，有16位受试者的CRP降低了40 mg / L，具有统计学意义（p = 0.0002），但是与13例正常范围相比，CRP仍然升高。结论。我们的研究表明，取决于牙源性感染的类型，治疗时间和治疗本身，CRP水平存在显着差异。尽管急性炎症引起较高的CRP值，但在收集到的数据中慢性炎症仍然很明显。

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